SQSTM1 anticorps (Sequestosome 1) (AA 1-440)

Details for Product anti-SQSTM1 Antibody No. ABIN522359, Fournisseur: Connectez-vous pour afficher
Antigène
  • SQSTM1
  • sqstm1
  • MGC79491
  • A170
  • OSIL
  • PDB3
  • ZIP3
  • p60
  • p62
  • p62B
  • OSF-6
  • Osi
  • STAP
  • ZIP
  • sb:cb621
  • zgc:85784
  • sequestosome 1
  • sequestosome 1 L homeolog
  • SQSTM1
  • sqstm1
  • Sqstm1
  • sqstm1.L
Épitope
AA 1-440, full length
68
42
36
36
25
20
19
16
15
14
12
12
11
9
9
8
7
6
5
4
4
4
3
3
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Reactivité
Humain
372
191
136
8
5
5
5
4
4
4
2
2
2
2
2
1
1
1
1
Hôte
Souris
313
50
6
3
Clonalité (Clone)
Monoclonal ()
Conjugué
Cet anticorp SQSTM1 est non-conjugé
19
17
16
12
12
12
5
5
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
3
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
ELISA, Western Blotting (WB)
309
121
102
95
72
70
38
36
28
22
18
13
4
3
2
Options
Fournisseur
Connectez-vous pour afficher
N° du produit (Fournisseur)
Connectez-vous pour afficher
Immunogène SQSTM1 (AAH03139.1, 1 a.a. ~ 440 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Immunogen sequence: MASLTVKAYL LGKEDAAREI RRFSFCCSPE PEAEAEAAAG PGPCERLLSR VAALFPALRP GGFQAHYRDE DGDLVAFSSD EELTMAMSYV KDDIFRIYIK EKKECRRDHR PPCAQEAPRN MVHPNVICDG CNGPVVGTRY KCSVCPDYDL CSVCEGKGLH RGHTKLAFPS PFGHLSEGFS HSRWLRKVKH GHFGWPGWEM GPPGNWSPRP PRAGEARPGP TAESASGPSE DPSVNFLKNV GESVAAALSP LGIEVDIDVE HGGKRSRLTP VSPESSSTEE KSSSQPSSCC SDPSKPGGNV EGATQSLAEQ MRKIALESEG RPEEQMESDN CSGGDDDWTH LSSKEVDPST GELQSLQMPE SEGPSSLDPS QEGPTGLKEA ALYPHLPPEA DPRLIESLSQ MLSMGFSDEG GWLTRLLQTK NYDIGAALDT IQYSKHPPPL
Clone 1C9
Isotype IgG3 kappa
 Réactivité croisée Humain
Plasmids, Primers & others Plasmids, Primers & others SQSTM1 products on genomics-online (e.g. as negative or positive controls)
Antigène
Autre désignation SQSTM1 (SQSTM1 Antibody Extrait)
Sujet Full Gene Name: sequestosome 1
Synonyms: A170,OSIL,PDB3,ZIP3,p60,p62,p62B
ID gène 8878
Pathways Signalisation NF-kappaB, Neurotrophin Signaling Pathway, Autophagy
Indications d'application Optimal working dilution should be determined by the investigator.
Commentaires

Product Quality tested by: Antibody Reactive Against Recombinant Protein.

Restrictions For Research Use only
Buffer In 1x PBS, pH 7.4
Conseil sur la manipulation Aliquot to avoid repeated freezing and thawing.
Stock -20 °C
Stockage commentaire Store at -20 °C or lower. Aliquot to avoid repeated freezing and thawing.
Images (Fournisseur)
ELISA image for anti-Sequestosome 1 (SQSTM1) (AA 1-440), (full length) antibody (ABIN522359) Detection limit for recombinant GST tagged SQSTM1 is approximately 3ng/ml as a captur...
 image for anti-Sequestosome 1 (SQSTM1) (AA 1-440), (full length) antibody (ABIN522359) Western Blot detection against Immunogen (74.14 KDa) .
Produit citée dans: Myeku, Clelland, Emrani, Kukushkin, Yu, Goldberg, Duff: "Tau-driven 26S proteasome impairment and cognitive dysfunction can be prevented early in disease by activating cAMP-PKA signaling." dans: Nature medicine, Vol. 22, Issue 1, pp. 46-53, 2016 (PubMed).

Notte, Ninane, Arnould, Michiels: "Hypoxia counteracts taxol-induced apoptosis in MDA-MB-231 breast cancer cells: role of autophagy and JNK activation." dans: Cell death & disease, Vol. 4, pp. e638, 2013 (PubMed).

Cosse, Rommelaere, Ninane, Arnould, Michiels: "BNIP3 protects HepG2 cells against etoposide-induced cell death under hypoxia by an autophagy-independent pathway." dans: Biochemical pharmacology, Vol. 80, Issue 8, pp. 1160-9, 2010 (PubMed).

Kirkin, Lamark, Sou, Bjørkøy, Nunn, Bruun, Shvets, McEwan, Clausen, Wild, Bilusic, Theurillat, Øvervatn, Ishii, Elazar, Komatsu, Dikic, Johansen: "A role for NBR1 in autophagosomal degradation of ubiquitinated substrates." dans: Molecular cell, Vol. 33, Issue 4, pp. 505-16, 2009 (PubMed).

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