DNMT1 anticorps (AA 637-650)

N° du produit ABIN531980

Détail du produit anti-DNMT1 anticorps

Antigène: DNMT1 (DNA (Cytosine-5)-Methyltransferase 1 (DNMT1))

Épitope: AA 637-650

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp DNMT1 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Chromatin Immunoprecipitation (ChIP), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Free Floating) (IHC (ff))

Fonction: Mouse monoclonal antibody raised against synthetic peptide of DNMT1.

Séquence: EKDDREDKEN AFKR

Réactivité croisée: Humain, Souris, Poisson zèbre (Danio rerio)

Immunogène: A synthetic peptide corresponding to amino acids 637-650 of human DNMT1.

Clone: 60B1220-1

Isotype: IgG1

Information d'application

Indications d'application: ChIP (1:20-1:1000)
Flow Cytometry
Immunocytochemistry (1:10)
Immunofluorescence (1:10)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:50-1:500)
Immunohistochemistry (Free floating sections) (1:500)
Immunohistoche

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In PBS (0.05 % sodium azide)

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

Références pour anticorps anti-DNMT1 (ABIN531980)

Du, Li, You, Wang, Wang, Cao, Hu, Liu: "DNA methylation in cystathionine-γ-lyase (CSE) gene promoter induced by ox-LDL in macrophages and in apoE knockout mice." dans: Biochemical and biophysical research communications, Vol. 469, Issue 3, pp. 776-82, (2016) (PubMed).

Li, Li, Du, Wang, You, Wang, Xu, Cheng, Cao, Liu, Hu: "Homocysteine Triggers Inflammatory Responses in Macrophages through Inhibiting CSE-H2S Signaling via DNA Hypermethylation of CSE Promoter." dans: International journal of molecular sciences, Vol. 16, Issue 6, pp. 12560-77, (2015) (PubMed).

Siouda, Frecha, Accardi, Yue, Cuenin, Gruffat, Manet, Herceg, Sylla, Tommasino: "Epstein-Barr virus down-regulates tumor suppressor DOK1 expression." dans: PLoS pathogens, Vol. 10, Issue 5, pp. e1004125, (2014) (PubMed).

Saidj, Cros, Hernandez-Vargas, Guarino, Sylla, Tommasino, Accardi: "Oncoprotein E7 from beta human papillomavirus 38 induces formation of an inhibitory complex for a subset of p53-regulated promoters." dans: Journal of virology, Vol. 87, Issue 22, pp. 12139-50, (2013) (PubMed).

Du, Zhou, Liu, Jiang, Wang, Hu, Qi, Zhong, Wang, Li: "Arsenic induces functional re-expression of estrogen receptor ? by demethylation of DNA in estrogen receptor-negative human breast cancer." dans: PLoS ONE, Vol. 7, Issue 4, pp. e35957, (2012) (PubMed).

Cheng, Auersperg, Leung: "Inhibition of p53 represses E-cadherin expression by increasing DNA methyltransferase-1 and promoter methylation in serous borderline ovarian tumor cells." dans: Oncogene, Vol. 30, Issue 37, pp. 3930-42, (2011) (PubMed).

Ji, Yang, Yu, Yuan, Hu, Zhang, Yang, Pang, Li, Lu, Fu, Chen, Lin, Chen, Zhuang: "Epigenetic silencing of O6-methylguanine DNA methyltransferase gene in NiS-transformed cells." dans: Carcinogenesis, Vol. 29, Issue 6, pp. 1267-75, (2008) (PubMed).

Guastafierro, Cecchinelli, Zampieri, Reale, Riggio, Sthandier, Zupi, Calabrese, Caiafa: "CCCTC-binding factor activates PARP-1 affecting DNA methylation machinery." dans: The Journal of biological chemistry, Vol. 283, Issue 32, pp. 21873-80, (2008) (PubMed).

Xia, Schneider-Stock, Diestel, Habold, Krueger, Roessner, Naumann, Lendeckel: "Helicobacter pylori regulates p21(WAF1) by histone H4 acetylation." dans: Biochemical and biophysical research communications, Vol. 369, Issue 2, pp. 526-31, (2008) (PubMed).

Villa, Pasini, Gutierrez, Morey, Occhionorelli, Viré, Nomdedeu, Jenuwein, Pelicci, Minucci, Fuks, Helin, Di Croce: "Role of the polycomb repressive complex 2 in acute promyelocytic leukemia." dans: Cancer cell, Vol. 11, Issue 6, pp. 513-25, (2007) (PubMed).

Mabaera, Greene, Richardson, Conine, Kozul, Lowrey: "Neither DNA hypomethylation nor changes in the kinetics of erythroid differentiation explain 5-azacytidine's ability to induce human fetal hemoglobin." dans: Blood, Vol. 111, Issue 1, pp. 411-20, (2007) (PubMed).

Détails sur DNMT1

Antigène: DNMT1 (DNA (Cytosine-5)-Methyltransferase 1 (DNMT1))

Autre désignation: DNMT1 (DNMT1 Produits)

Synonymes: anticorps cb1075, anticorps cb983, anticorps dmnt1, anticorps fb05h01, anticorps mta, anticorps wu:fb05h01, anticorps ADCADN, anticorps AIM, anticorps CXXC9, anticorps DNMT, anticorps HSN1E, anticorps MCMT, anticorps DDM2, anticorps DECREASED DNA METHYLATION 2, anticorps DMT01, anticorps DMT1, anticorps DNA METHYLTRANSFERASE, anticorps DNA METHYLTRANSFERASE 01, anticorps DNA METHYLTRANSFERASE 1, anticorps MET2, anticorps METHYLTRANSFERASE 2, anticorps METHYLTRANSFERASE I, anticorps METI, anticorps methyltransferase 1, anticorps Cxxc9, anticorps Dnmt, anticorps Dnmt1o, anticorps MTase, anticorps Met-1, anticorps Met1, anticorps MommeD2, anticorps m.MmuI, anticorps DNA methyltransferase 1, anticorps DNA (cytosine-5-)-methyltransferase 1, anticorps methyltransferase 1, anticorps DNA methyltransferase (cytosine-5) 1, anticorps DNMT1, anticorps dnmt1, anticorps Dnmt1, anticorps MET1

ID gène: 1786

Pathways: SARS-CoV-2 Protein Interactome, Phosphorylation & l'infection par le SRAS-CoV-2