BAD anticorps (BCL2-Associated Agonist of Cell Death) (pSer118)

Details for Product anti-BAD Antibody No. ABIN532014
Antigène
Épitope
pSer118, pSer155
63
58
53
52
46
46
45
38
28
24
24
18
18
18
18
18
18
18
17
17
17
17
17
17
17
17
17
17
17
17
15
14
12
11
10
10
10
10
10
9
7
6
4
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivité
Souris
797
473
325
20
19
8
5
4
3
2
2
1
1
1
1
1
Hôte
Souris
989
40
2
1
Clonalité (Clone)
Monoclonal ()
Conjugué
Cet anticorp BAD est non-conjugé
74
67
67
63
62
61
12
12
12
12
12
12
6
6
6
6
6
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
Application
Western Blotting (WB)
548
522
383
334
110
79
35
35
19
19
8
7
5
3
2
1
1
1
1
Options
Fonction Mouse monoclonal antibody raised against synthetic phosphopeptide of Bad.
Immunogène Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding S155 of mouse Bad.
Clone 27AT381
Isotype IgG1
Antigène
Autre désignation Bcl-2-like 8 (BAD Antibody Extrait)
Pathways Signalisation MAPK, Signalisation PI3K-Akt, Signalisation RTK, Apoptose, Fc-epsilon Receptor Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Hepatitis C, CXCR4-mediated Signaling Events
Indications d'application Western Blot (1:100-500)
The optimal working dilution should be determined by the end user.
Restrictions For Research Use only
Buffer In PBS (0.09 % sodium azide)
Stock 4 °C,-20 °C
Stockage commentaire Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Images (Fournisseur)
Image no. 1 for anti-BCL2-Associated Agonist of Cell Death (BAD) (pSer118), (pSer155) antibody (ABIN532014) Western analysis of cell extracts from 293 cells transfected with Flag-Bad, using Bad...
Produit citée dans: Quoyer, Longuet, Broca, Linck, Costes, Varin, Bockaert, Bertrand, Dalle: "GLP-1 mediates antiapoptotic effect by phosphorylating Bad through a beta-arrestin 1-mediated ERK1/2 activation in pancreatic beta-cells." dans: The Journal of biological chemistry, Vol. 285, Issue 3, pp. 1989-2002, 2010 (PubMed).

Frenzel, Labi, Chmelewskij, Ploner, Geley, Fiegl, Tzankov, Villunger: "Suppression of B-cell lymphomagenesis by the BH3-only proteins Bmf and Bad." dans: Blood, Vol. 115, Issue 5, pp. 995-1005, 2010 (PubMed).

Polzien, Baljuls, Rennefahrt, Fischer, Schmitz, Zahedi, Sickmann, Metz, Albert, Benz, Hekman, Rapp: "Identification of novel in vivo phosphorylation sites of the human proapoptotic protein BAD: pore-forming activity of BAD is regulated by phosphorylation." dans: The Journal of biological chemistry, Vol. 284, Issue 41, pp. 28004-20, 2009 (PubMed).