EPAS1 anticorps (AA 535-631)

N° du produit ABIN534071

Détail du produit anti-EPAS1 anticorps

Antigène: EPAS1 (Endothelial PAS Domain Protein 1 (EPAS1))

Épitope: AA 535-631

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp EPAS1 est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: Mouse monoclonal antibody raised against partial recombinant EPAS1.

Specificité: This antibody is specific to HIF-2 alpha and does not cross-react with HIF-1 alpha.

Réactivité croisée: Humain, Souris, Rat

Immunogène: Recombinant protein corresponding to amino acids 535-631 of human EPAS1.

Clone: Ep190b

Isotype: IgG1

Information d'application

Indications d'application: ELISA (1:1000)
Flow Cytometry (1 μg/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:150-1:300)
Western Blot (1:500)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In PBS (0.09 % sodium azide)

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Store at -20°C or -80°C.
Aliquot to avoid repeated freezing and thawing.

Références pour anticorps anti-EPAS1 (ABIN534071)

Chintalapudi, Markiewicz, Kose, Dammai, Champion, Hoda, Trojanowska, Hsu: "Cyr61/CCN1 and CTGF/CCN2 mediate the proangiogenic activity of VHL-mutant renal carcinoma cells." dans: Carcinogenesis, Vol. 29, Issue 4, pp. 696-703, (2008) (PubMed).

Kubo, Sugita, Shimose, Matsuo, Arihiro, Ochi: "Expression of hypoxia-inducible factor-1alpha and its relationship to tumour angiogenesis and cell proliferation in cartilage tumours." dans: The Journal of bone and joint surgery. British volume, Vol. 90, Issue 3, pp. 364-70, (2008) (PubMed).

Bernhardt, Wiesener, Weidemann, Schmitt, Weichert, Lechler, Campean, Ong, Willam, Gretz, Eckardt: "Involvement of hypoxia-inducible transcription factors in polycystic kidney disease." dans: The American journal of pathology, Vol. 170, Issue 3, pp. 830-42, (2007) (PubMed).

Sutphin, Chan, Li, Turcotte, Krieg, Giaccia: "Targeting the loss of the von Hippel-Lindau tumor suppressor gene in renal cell carcinoma cells." dans: Cancer research, Vol. 67, Issue 12, pp. 5896-905, (2007) (PubMed).

Détails sur EPAS1

Antigène: EPAS1 (Endothelial PAS Domain Protein 1 (EPAS1))

Autre désignation: HIF2A / HIF2 alpha (EPAS1 Produits)

Synonymes: anticorps EPAS1, anticorps ECYT4, anticorps HIF2A, anticorps HLF, anticorps MOP2, anticorps PASD2, anticorps bHLHe73, anticorps HIF-2alpha, anticorps HRF, anticorps Hif2a, anticorps bhlhe73, anticorps ecyt4, anticorps hif2, anticorps hif2a, anticorps hif2alpha, anticorps hlf, anticorps mop2, anticorps pasd2, anticorps EPAS, anticorps EPAS-1, anticorps endothelial PAS domain protein 1, anticorps endothelial PAS domain protein 1 L homeolog, anticorps EPAS1, anticorps epas1, anticorps Epas1, anticorps epas1.L

ID gène: 2034

Pathways: Signaling Events mediated by VEGFR1 and VEGFR2, L'effet Warburg