ARNT anticorps (AA 496-789)

N° du produit ABIN534093

Détail du produit anti-ARNT anticorps

Antigène: ARNT (Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT))

Épitope: AA 496-789

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ARNT est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: Mouse monoclonal antibody raised against partial recombinant ARNT.

Specificité: This antibody is specific to HIF-1 beta /ARNT.

Réactivité croisée: Boeuf (Vache), Furet, Humain, Souris, Rat, Mouton

Attributs du produit: Antibody Reactive Against Recombinant Protein.

Immunogène: Recombinant protein corresponding to amino acids 496-789 of human ARNT.

Clone: H1beta234

Isotype: IgG1

Information d'application

Indications d'application: Western Blot (1:500)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:100)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In PBS (0.05 % sodium azide)

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Store at -20°C or -80°C.
Aliquot to avoid repeated freezing and thawing.

Références pour anticorps anti-ARNT (ABIN534093)

Do, Fink, Jensen, Gautier, Parlesak: "TLR2 controls intestinal carcinogen detoxication by CYP1A1." dans: PLoS ONE, Vol. 7, Issue 3, pp. e32309, (2012) (PubMed).

Kransler, McGarrigle, Swartz, Olson: "Lung development in the Holtzman rat is adversely affected by gestational exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin." dans: Toxicological sciences : an official journal of the Society of Toxicology, Vol. 107, Issue 2, pp. 498-511, (2009) (PubMed).

Lauzier, Robitaille, Chan, Giaccia, Richard: "(2R)-[(4-Biphenylylsulfonyl)amino]-N-hydroxy-3-phenylpropionamide (BiPS), a matrix metalloprotease inhibitor, is a novel and potent activator of hypoxia-inducible factors." dans: Molecular pharmacology, Vol. 74, Issue 1, pp. 282-8, (2008) (PubMed).

Puppo, Battaglia, Ottaviano, Delfino, Ribatti, Varesio, Bosco: "Topotecan inhibits vascular endothelial growth factor production and angiogenic activity induced by hypoxia in human neuroblastoma by targeting hypoxia-inducible factor-1alpha and -2alpha." dans: Molecular cancer therapeutics, Vol. 7, Issue 7, pp. 1974-84, (2008) (PubMed).

Aminova, Siddiq, Ratan et al.: "Antioxidants, HIF prolyl hydroxylase inhibitors or short interfering RNAs to BNIP3 or PUMA, can prevent prodeath effects of the transcriptional activator, HIF-1alpha, in a mouse hippocampal neuronal ..." dans: Antioxidants & redox signaling, Vol. 10, Issue 12, pp. 1989-98, (2008) (PubMed).

Baek, Liu, McDonald, Wesley, Hubbi, Byun, Semenza: "Spermidine/spermine-N1-acetyltransferase 2 is an essential component of the ubiquitin ligase complex that regulates hypoxia-inducible factor 1alpha." dans: The Journal of biological chemistry, Vol. 282, Issue 32, pp. 23572-80, (2007) (PubMed).

Détails sur ARNT

Antigène: ARNT (Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT))

Autre désignation: HIF1 beta / ARNT (ARNT Produits)

Synonymes: anticorps HIF-1-beta, anticorps HIF-1beta, anticorps HIF1-beta, anticorps HIF1B, anticorps HIF1BETA, anticorps TANGO, anticorps bHLHe2, anticorps D3Ertd557e, anticorps Drnt, anticorps ESTM42, anticorps Hif1b, anticorps W08714, anticorps mKIAA4051, anticorps Arnt1, anticorps ARNT, anticorps zgc:136664, anticorps arnt1, anticorps hif1b, anticorps tango, anticorps xArnt, anticorps hif1beta, anticorps hif-1beta, anticorps arnt.2, anticorps MGC68805, anticorps aryl hydrocarbon receptor nuclear translocator, anticorps aryl hydrocarbon receptor nuclear translocator S homeolog, anticorps ARNT, anticorps Arnt, anticorps arnt, anticorps arnt.S

ID gène: 405

Pathways: Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Regulation of Carbohydrate Metabolic Process, Signaling Events mediated by VEGFR1 and VEGFR2, L'effet Warburg