RAD51C anticorps

N° du produit ABIN534110

Détail du produit anti-RAD51C anticorps

Antigène: RAD51C (DNA Repair Protein RAD51 Homolog 3 (RAD51C))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp RAD51C est non-conjugé

Application: Western Blotting (WB)

Fonction: Mouse monoclonal antibody raised against recombinant RAD51C.

Specificité: This antibody is specific to Rad51C.

Réactivité croisée: Humain, Souris

Attributs du produit: Antibody Reactive Against Recombinant Protein.

Immunogène: Recombinant His fusion protein corresponding to human RAD51C.

Clone: 2H11-6

Isotype: IgG1

Information d'application

Indications d'application: Western Blot (1:1000)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In PBS (0.02 % sodium azide)

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store at 4°C. Do not freeze.

Références pour anticorps anti-RAD51C (ABIN534110)

Shammas, Shmookler Reis, Koley, Batchu, Li, Munshi: "Dysfunctional homologous recombination mediates genomic instability and progression in myeloma." dans: Blood, Vol. 113, Issue 10, pp. 2290-7, (2009) (PubMed).

Chan, Koritzinsky, Zhao, Bindra, Glazer, Powell, Belmaaza, Wouters, Bristow: "Chronic hypoxia decreases synthesis of homologous recombination proteins to offset chemoresistance and radioresistance." dans: Cancer research, Vol. 68, Issue 2, pp. 605-14, (2008) (PubMed).

Kuznetsov, Pellegrini, Shuda, Fernandez-Capetillo, Liu, Martin, Burkett, Southon, Pati, Tessarollo, West, Donovan, Nussenzweig, Sharan: "RAD51C deficiency in mice results in early prophase I arrest in males and sister chromatid separation at metaphase II in females." dans: The Journal of cell biology, Vol. 176, Issue 5, pp. 581-92, (2007) (PubMed).

Fan, Kumaravel, Jalali, Marrano, Squire, Bristow: "Defective DNA strand break repair after DNA damage in prostate cancer cells: implications for genetic instability and prostate cancer progression." dans: Cancer research, Vol. 64, Issue 23, pp. 8526-33, (2004) (PubMed).

Maacke, Hundertmark, Miska, Voss, Kalthoff, Stürzbecher: "Autoantibodies in sera of pancreatic cancer patients identify recombination factor Rad51 as a tumour-associated antigen." dans: Journal of cancer research and clinical oncology, Vol. 128, Issue 4, pp. 219-22, (2002) (PubMed).

Détails sur RAD51C

Antigène: RAD51C (DNA Repair Protein RAD51 Homolog 3 (RAD51C))

Autre désignation: RAD51C (RAD51C Produits)

ID gène: 5889

Pathways: Réparation de l'ADN