CD147 anticorps

N° du produit ABIN535271

Détail du produit anti-CD147 anticorps

Antigène: CD147 (BSG) (Basigin (Ok Blood Group) (BSG))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD147 est non-conjugé

Application: Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: Mouse monoclonal antibody raised against recombinant BSG.

Specificité: This antibody recognizes extracellular Ig domain D1 of BSG (Neurothelin), a 50-60 KDa type I transmembrane glycoprotein primarily expressed on all leukocytes, redblood cells, platelets and endothelial cells, it is not expressed by resting lymphocytes. This antibody is a high-affinity antibody capable of binding to unstimulated peripheral blood T cells.

Réactivité croisée: Humain, Porc

Immunogène: Recombinant protein corresponding to human BSG.

Clone: MEM-M6-2

Isotype: IgG2b

Information d'application

Indications d'application: Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (10 μg/mL)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In PBS, pH 7.4 (0.09 % sodium azide)

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store at 4°C. Do not freeze.
Aliquot to avoid repeated freezing and thawing.

Références pour anticorps anti-CD147 (ABIN535271)

Schmidt, Bültmann, Fischel, Gillitzer, Cullen, Walch, Jost, Ungerer, Tolley, Lindemann, Gawaz, Schömig, May: "Extracellular matrix metalloproteinase inducer (CD147) is a novel receptor on platelets, activates platelets, and augments nuclear factor kappaB-dependent inflammation in monocytes." dans: Circulation research, Vol. 102, Issue 3, pp. 302-9, (2008) (PubMed).

Melchior, Denys, Deligny, Mazurier, Allain: "Cyclophilin B induces integrin-mediated cell adhesion by a mechanism involving CD98-dependent activation of protein kinase C-delta and p44/42 mitogen-activated protein kinases." dans: Experimental cell research, Vol. 314, Issue 3, pp. 616-28, (2008) (PubMed).

Ruiz, Castro-Castro, Bustelo: "CD147 inhibits the nuclear factor of activated T-cells by impairing Vav1 and Rac1 downstream signaling." dans: The Journal of biological chemistry, Vol. 283, Issue 9, pp. 5554-66, (2008) (PubMed).

Détails sur CD147

Antigène: CD147 (BSG) (Basigin (Ok Blood Group) (BSG))

Autre désignation: CD147 (BSG Produits)

Synonymes: anticorps EMMPRIN, anticorps RPE7, anticorps 5F7, anticorps CD147, anticorps M6, anticorps OK, anticorps TCSF, anticorps AI115436, anticorps AI325119, anticorps HT-7, anticorps 5A11, anticorps CE9, anticorps HT7, anticorps Ox47R, anticorps basignin, anticorps wu:fb26a05, anticorps wu:fo98e12, anticorps bsg, anticorps prso03, anticorps basigin (Ok blood group), anticorps basigin, anticorps basigin (Ok blood group) S homeolog, anticorps BSG, anticorps Bsg, anticorps bsg, anticorps bsg.S

ID gène: 682

Pathways: S100 Proteins