STAT1 anticorps (Signal Transducer and Activator of Transcription 1, 91kDa) (pSer727)

Details for Product anti-STAT1 Antibody No. ABIN535279
Antigène
Épitope
pSer727
95
66
49
17
17
15
8
8
8
8
7
7
7
5
5
4
4
4
4
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivité
Humain
535
291
265
32
30
26
22
21
15
12
10
6
6
5
2
1
1
1
1
1
Hôte
Souris
455
102
2
2
1
Clonalité (Clone)
Monoclonal ()
Conjugué
Cet anticorp STAT1 est non-conjugé
18
14
13
11
11
11
11
11
11
6
6
5
5
5
5
5
4
2
2
2
Application
Immunoprecipitation (IP)
431
190
164
106
95
65
43
23
20
9
7
5
5
1
1
Options
Fonction Mouse monoclonal antibody raised against synthetic phosphopeptide of STAT1.
Immunogène Synthetic phosphopeptide corresponding to amino acids 721-733 residues surrounding S727 of STAT1.
Clone PSM1
Isotype IgG1
Specificité This antibody recognizes transcriptional factor STAT1 (91 KDa) activated byphosphorylation at Ser727.
Antigène
Autre désignation STAT1 (STAT1 Antibody Extrait)
Pathways Signalistation JAK/STAT, Signalisation RTK, Interferon-gamma Pathway, Response to Growth Hormone Stimulus, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity, Hepatitis C, CXCR4-mediated Signaling Events
Indications d'application The optimal working dilution should be determined by the end user.
Restrictions For Research Use only
Buffer In PBS, pH 7.4 (0.09 % sodium azide)
Stock 4 °C
Stockage commentaire Store at 4°C. Do not freeze.
Aliquot to avoid repeated freezing and thawing.
Images (Fournisseur)
Image no. 1 for anti-Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) (pSer727) antibody (ABIN535279) Western Blotting analysis (reducing conditions) of phosphorylated STAT1 (Ser727) in I...
Produit citée dans: Soond, Townsend, Barry, Knight, Latchman, Stephanou: "ERK and the F-box protein betaTRCP target STAT1 for degradation." dans: The Journal of biological chemistry, Vol. 283, Issue 23, pp. 16077-83, 2008 (PubMed).

Kovarik, Boudny, Kocak, Lauerova, Fait, Vagundova: "Malignant melanoma associates with deficient IFN-induced STAT 1 phosphorylation." dans: International journal of molecular medicine, Vol. 12, Issue 3, pp. 335-40, 2003 (PubMed).

Boudný, Kocák, Lauerová, Kovarík: "Interferon inducibility of STAT 1 activation and its prognostic significance in melanoma patients." dans: Folia biologica, Vol. 49, Issue 4, pp. 142-6, 2003 (PubMed).