Mouse monoclonal antibody raised against synthetic peptide of INPP5D.
Specificité
This antibody reacts with SHIP-1, a phosphoinositide phosphatase largely confined to hematopoietic cells. Multiple forms of SHIP-1 have been reported with molecular weights of 110, 125, 130, 135 and 145 KDa.
Réactivité croisée
Humain
Immunogène
A synthetic peptide corresponding to N-terminus human INPP5D.
INPP5D
Reactivité: Humain, Souris, Rat
WB, ELISA
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
Flow Cytometry (2-5 μg/mL) The optimal working dilution should be determined by the end user.
Restrictions
For Research Use only
Format
Liquid
Buffer
In PBS, pH 7.4 (0.09 % sodium azide)
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C
Stockage commentaire
Store at 4°C. Do not freeze. Aliquot to avoid repeated freezing and thawing.
Rotblat, Yizhar, Haklai, Ashery, Kloog: "Ras and its signals diffuse through the cell on randomly moving nanoparticles." dans: Cancer research, Vol. 66, Issue 4, pp. 1974-81, (2006) (PubMed).
Roy, Plowman, Rotblat, Prior, Muncke, Grainger, Parton, Henis, Kloog, Hancock: "Individual palmitoyl residues serve distinct roles in H-ras trafficking, microlocalization, and signaling." dans: Molecular and cellular biology, Vol. 25, Issue 15, pp. 6722-33, (2005) (PubMed).
Rotblat, Prior, Muncke, Parton, Kloog, Henis, Hancock: "Three separable domains regulate GTP-dependent association of H-ras with the plasma membrane." dans: Molecular and cellular biology, Vol. 24, Issue 15, pp. 6799-810, (2004) (PubMed).