CD72 anticorps (PE)

N° du produit ABIN536036

Détail du produit anti-CD72 anticorps (PE)

Antigène: CD72 (CD72 Molecule (CD72))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD72 est conjugé à/à la PE

Application: Flow Cytometry (FACS), Immunoprecipitation (IP)

Fonction: Mouse monoclonal antibody raised against native CD72.

Specificité: This antibody 3F3 reacts with CD72, a 39-43 KDa type II membrane glycoprotein (C-type lectin family). CD72 is a pan-B cell marker expressed throughout the B lymphocytes diferentiation with the exception of plasma cells, it is also present on follicular dendritic cells.

Réactivité croisée: Humain

Immunogène: Native purified CD72 from normal human lymphocytes from lymph node.

Clone: 3F3

Isotype: IgG2b

Information d'application

Indications d'application: Flow Cytometry (20 µL in human blood cells 100 µL in whole blood or 10⁶ cells in a suspension)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In PBS (0.2 % BSA, 0.09 % sodium azide)

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store in the dark at 4°C. Do not freeze.
Avoid prolonged exposure to light.
Aliquot to avoid repeated freezing and thawing.

Références pour anticorps anti-CD72 (PE) (ABIN536036)

Mizrahi, Markel, Porgador, Bushkin, Mandelboim: "CD100 on NK cells enhance IFNgamma secretion and killing of target cells expressing CD72." dans: PLoS ONE, Vol. 2, Issue 9, pp. e818, (2007) (PubMed).

Kumanogoh, Shikina, Watanabe, Takegahara, Suzuki, Yamamoto, Takamatsu, Prasad, Mizui, Toyofuku, Tamura, Watanabe, Parnes, Kikutani: "Requirement for CD100-CD72 interactions in fine-tuning of B-cell antigen receptor signaling and homeostatic maintenance of the B-cell compartment." dans: International immunology, Vol. 17, Issue 10, pp. 1277-82, (2005) (PubMed).

Kumanogoh, Kikutani: "The CD100-CD72 interaction: a novel mechanism of immune regulation." dans: Trends in immunology, Vol. 22, Issue 12, pp. 670-6, (2001) (PubMed).

Détails sur CD72

Antigène: CD72 (CD72 Molecule (CD72))

Autre désignation: CD72 (CD72 Produits)

Synonymes: anticorps CD72c, anticorps Ly-19, anticorps Ly-32, anticorps Ly-m19, anticorps Lyb-2, anticorps CD72b, anticorps LYB2, anticorps CD72 antigen, anticorps CD72 molecule, anticorps Cd72, anticorps CD72

ID gène: 971

Pathways: BCR Signaling