LAT2 anticorps (Linker For Activation of T Cells Family, Member 2) (PE)

Details for Product anti-LAT2 Antibody No. ABIN536095
Antigène
  • LAB
  • NTAL
  • WBSCR15
  • WBSCR5
  • WSCR5
  • LAT2
  • MGC139435
  • Ntal
  • Wbscr5
  • AW125574
  • Wbscr15
  • linker for activation of T-cells family member 2
  • linker for activation of T cells family, member 2
  • LAT2
  • Lat2
Reactivité
Humain
112
43
29
3
3
2
1
1
1
1
1
Hôte
Souris
103
28
7
Clonalité (Clone)
Monoclonal ()
Conjugué
Cet anticorp LAT2 est conjugé à/à la PE
8
6
4
3
3
3
2
2
2
2
2
2
Application
Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunoprecipitation (IP), Western Blotting (WB)
123
39
31
31
16
14
14
6
3
3
2
1
1
Options
Fonction Mouse monoclonal antibody raised against partial recombinant LAT2.
Immunogène Recombinant protein corresponding to partial human LAT2.
Clone NAP-07
Isotype IgG1
Specificité This antibody reacts with Non-T cell activation linker (NTAL), also known as LAB (linker of activated B cells), a 25-30 KDa transmembrane adaptor protein present in membrane microdomains (rafts) of B lymphocytes, NK cells and myeloid cells.
 Réactivité croisée Souris
Plasmids, Primers & others Plasmids, Primers & others LAT2 products on genomics-online (e.g. as negative or positive controls)
Antigène
Autre désignation LAT2 / WBSCR15 (LAT2 Antibody Extrait)
Pathways Fc-epsilon Receptor Signaling Pathway
Indications d'application Flow Cytometry (1:30)
The optimal working dilution should be determined by the end user.
Restrictions For Research Use only
Concentration 0.1 mg/mL
Buffer In PBS (0.2 % BSA, 0.09 % sodium azide)
Stock 4 °C
Stockage commentaire Store in the dark at 4°C. Do not freeze.
Avoid prolonged exposure to light.
Aliquot to avoid repeated freezing and thawing.
Produit citée dans: Lebduska, Korb, T?mová, Heneberg, Dráber: "Topography of signaling molecules as detected by electron microscopy on plasma membrane sheets isolated from non-adherent mast cells." dans: Journal of immunological methods, Vol. 328, Issue 1-2, pp. 139-51, 2007 (PubMed).

Tkaczyk, Horejsi, Iwaki, Draber, Samelson, Satterthwaite, Nahm, Metcalfe, Gilfillan: "NTAL phosphorylation is a pivotal link between the signaling cascades leading to human mast cell degranulation following Kit activation and Fc epsilon RI aggregation." dans: Blood, Vol. 104, Issue 1, pp. 207-14, 2004 (PubMed).

Volná, Lebduska, Dráberová, Símová, Heneberg, Boubelík, Bugajev, Malissen, Wilson, Horejsí, Malissen, Dráber: "Negative regulation of mast cell signaling and function by the adaptor LAB/NTAL." dans: The Journal of experimental medicine, Vol. 200, Issue 8, pp. 1001-13, 2004 (PubMed).

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