FOXO1 anticorps (pSer256)

N° du produit ABIN539166

Détail du produit anti-FOXO1 anticorps

Antigène: FOXO1 (Forkhead Box O1 (FOXO1))

Épitope: pSer256

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FOXO1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: Rabbit polyclonal antibody raised against synthetic phosphopeptide of FOXO1.

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Antibody Reactive Against Synthetic Peptide.

Immunogène: Synthetic phosphopeptide corresponding to residues surrounding S256 of human FOXO1.

Information d'application

Indications d'application: Immunohistochemistry (1:50-1:100)
Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: In PBS (without Mg²⁺ and Ca²⁺), 150 mM NaCl, pH 7.4 (50 % glycerol, 0.02 % sodium azide)

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C.
Aliquot to avoid repeated freezing and thawing.

Références pour anticorps anti-FOXO1 (ABIN539166)

Sajan, Ivey, Farese: "BMI-related progression of atypical PKC-dependent aberrations in insulin signaling through IRS-1, Akt, FoxO1 and PGC-1α in livers of obese and type 2 diabetic humans." dans: Metabolism: clinical and experimental, Vol. 64, Issue 11, pp. 1454-65, (2015) (PubMed).

Sajan, Ivey, Lee, Mastorides, Jurczak, Samuels, Shulman, Braun, Leitges, Farese: "PKC? haploinsufficiency prevents diabetes by a mechanism involving alterations in hepatic enzymes." dans: Molecular endocrinology (Baltimore, Md.), Vol. 28, Issue 7, pp. 1097-107, (2014) (PubMed).

Sajan, Ivey, Lee, Farese: "Hepatic insulin resistance in ob/ob mice involves increases in ceramide, aPKC activity, and selective impairment of Akt-dependent FoxO1 phosphorylation." dans: Journal of lipid research, Vol. 56, Issue 1, pp. 70-80, (2014) (PubMed).

Détails sur FOXO1

Antigène: FOXO1 (Forkhead Box O1 (FOXO1))

Autre désignation: FOXO1A (FOXO1 Produits)

Synonymes: anticorps FKH1, anticorps FKHR, anticorps FOXO1A, anticorps FoxO1a.1, anticorps foxo1, anticorps zgc:153388, anticorps Fkhr, anticorps Foxo1a, anticorps AI876417, anticorps Afxh, anticorps Fkhr1, anticorps fkh1, anticorps fkhr, anticorps foxo1a, anticorps xFoxO1, anticorps FoxO1A, anticorps foxo1a.2, anticorps forkhead box O1, anticorps forkhead box O1 a, anticorps forkhead box O1 L homeolog, anticorps forkhead box O1 b, anticorps FOXO1, anticorps foxo1a, anticorps Foxo1, anticorps foxo1, anticorps foxo1.L, anticorps foxo1b

ID gène: 2308

Pathways: Signalisation PI3K-Akt, Cycle Cellulaire, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Carbohydrate Metabolic Process, CXCR4-mediated Signaling Events, BCR Signaling