SMAD2 anticorps (Internal Region)

N° du produit ABIN539483

Détail du produit anti-SMAD2 anticorps

Antigène: SMAD2 (SMAD, Mothers Against DPP Homolog 2 (SMAD2))

Épitope: Internal Region

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SMAD2 est non-conjugé

Application: Western Blotting (WB), ELISA

Fonction: Rabbit polyclonal antibody raised against synthetic peptide of SMAD2.

Specificité: This antibody is Smad2 specific, and reactivity to other Smad proteins (specifically Smad1, Smad3, Smad4, and Smad7) is not detected in over-expressed cell lysates.

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Antibody Reactive Against Synthetic Peptide.

Immunogène: A synthetic peptide corresponding to internal region of human SMAD2.

Information d'application

Indications d'application: ELISA (1:100000)
Western Blot (1:1000-1:3000)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 20 mM KH₂PO₄, 150 mM NaCl, pH 7.2 (0.01 % sodium azide)

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

Références pour anticorps anti-SMAD2 (ABIN539483)

Bruna, Darken, Rojo, Ocaña, Peñuelas, Arias, Paris, Tortosa, Mora, Baselga, Seoane: "High TGFbeta-Smad activity confers poor prognosis in glioma patients and promotes cell proliferation depending on the methylation of the PDGF-B gene." dans: Cancer cell, Vol. 11, Issue 2, pp. 147-60, (2007) (PubMed).

Liapis, Mylona, Alexandrou, Giannopoulou, Nikolaou, Markaki, Keramopoulos, Nakopoulou: "Effect of the different phosphorylated Smad2 protein localizations on the invasive breast carcinoma phenotype." dans: APMIS : acta pathologica, microbiologica, et immunologica Scandinavica, Vol. 115, Issue 2, pp. 104-14, (2007) (PubMed).

Yang, Huang, Chen, Lin, Chen: "Leptin augments myofibroblastic conversion and fibrogenic activity of human peritoneal mesothelial cells: a functional implication for peritoneal fibrosis." dans: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, Vol. 22, Issue 3, pp. 756-62, (2007) (PubMed).

Détails sur SMAD2

Antigène: SMAD2 (SMAD, Mothers Against DPP Homolog 2 (SMAD2))

Autre désignation: SMAD2 (SMAD2 Produits)

Synonymes: anticorps JV18, anticorps JV18-1, anticorps MADH2, anticorps MADR2, anticorps hMAD-2, anticorps hSMAD2, anticorps jv18, anticorps Xmad2, anticorps madh2, anticorps madr2, anticorps XSmad2, anticorps hmad-2, anticorps hsmad2, anticorps jv18-1, anticorps smad-2, anticorps fj43c06, anticorps wu:fj43c06, anticorps 7120426M23Rik, anticorps Madh2, anticorps Madr2, anticorps Smad-2, anticorps mMad2, anticorps MAD homolog 2, anticorps Mothers against DPP homolog 2, anticorps SMAD 2, anticorps Smad2, anticorps SMAD family member 2, anticorps SMAD family member 2-Z, anticorps SMAD family member 2 S homeolog, anticorps SMAD2, anticorps SMAD2Z, anticorps smad2, anticorps smad2.S, anticorps Smad2

ID gène: 4087

Pathways: Cycle Cellulaire, Hormone Transport, Chromatin Binding, Protein targeting to Nucleus