EPAS1 anticorps (C-Term)

N° du produit ABIN540396

Détail du produit anti-EPAS1 anticorps

Antigène: EPAS1 (Endothelial PAS Domain Protein 1 (EPAS1))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Poisson, Primate

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EPAS1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP), Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Chromatin Immunoprecipitation (ChIP), Gel Shift (GS)

Fonction: Rabbit polyclonal antibody raised against synthetic peptide of EPAS1.

Specificité: Specific for HIF-2 alpha/EPAS. Does not cross-react with HIF-1 alpha.

Réactivité croisée: Poisson, Humain, Souris, Primate, Rat

Immunogène: A synthetic peptide corresponding to C-terminus of human and mouse EPAS1/Epas1.

Information d'application

Indications d'application: ChIP (1:10-1:500)
ELISA (1:100-1:2000)
Flow Cytometry
Gel Supershift Assay
Immunocytochemistry (1:100)
Immunofluorescence (1:100)
Immunohistochemistry (Frozen sections)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sectio

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In PBS (0.05 % sodium azide)

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C.
Aliquot to avoid repeated freezing and thawing.

Références pour anticorps anti-EPAS1 (ABIN540396)

Ruf, Moch, Schraml: "PD-L1 expression is regulated by hypoxia inducible factor in clear cell renal cell carcinoma." dans: International journal of cancer, Vol. 139, Issue 2, pp. 396-403, (2016) (PubMed).

Wacker, Sachs, Knaup, Wiesener, Weiske, Huber, Akçetin, Behrens: "Key role for activin B in cellular transformation after loss of the von Hippel-Lindau tumor suppressor." dans: Molecular and cellular biology, Vol. 29, Issue 7, pp. 1707-18, (2009) (PubMed).

Lee, Qian, Rey, Wei, Liu, Semenza: "Anthracycline chemotherapy inhibits HIF-1 transcriptional activity and tumor-induced mobilization of circulating angiogenic cells." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 7, pp. 2353-8, (2009) (PubMed).

Walter, Etienne-Selloum, Brasse, Schleiffer, Bekaert, Vanhoutte, Beretz, Schini-Kerth: "Red wine polyphenols prevent acceleration of neovascularization by angiotensin II in the ischemic rat hindlimb." dans: The Journal of pharmacology and experimental therapeutics, Vol. 329, Issue 2, pp. 699-707, (2009) (PubMed).

Lomb, Desouza, Franklin, Freeman et al.: "Prolyl hydroxylase inhibitors depend on extracellular glucose and hypoxia-inducible factor (HIF)-2alpha to inhibit cell death caused by nerve growth factor (NGF) deprivation: evidence that HIF-2alpha ..." dans: Molecular pharmacology, Vol. 75, Issue 5, pp. 1198-209, (2009) (PubMed).

Sears, Hoppe, Ebrahem, Anand-Apte: "Prolyl hydroxylase inhibition during hyperoxia prevents oxygen-induced retinopathy." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 50, pp. 19898-903, (2008) (PubMed).

Détails sur EPAS1

Antigène: EPAS1 (Endothelial PAS Domain Protein 1 (EPAS1))

Autre désignation: HIF2A / HIF2 alpha (EPAS1 Produits)

Synonymes: anticorps EPAS1, anticorps ECYT4, anticorps HIF2A, anticorps HLF, anticorps MOP2, anticorps PASD2, anticorps bHLHe73, anticorps HIF-2alpha, anticorps HRF, anticorps Hif2a, anticorps bhlhe73, anticorps ecyt4, anticorps hif2, anticorps hif2a, anticorps hif2alpha, anticorps hlf, anticorps mop2, anticorps pasd2, anticorps EPAS, anticorps EPAS-1, anticorps endothelial PAS domain protein 1, anticorps endothelial PAS domain protein 1 L homeolog, anticorps EPAS1, anticorps epas1, anticorps Epas1, anticorps epas1.L

ID gène: 2034, 13819

Pathways: Signaling Events mediated by VEGFR1 and VEGFR2, L'effet Warburg