INSIG1 anticorps (AA 1-100)

N° du produit ABIN540703

Détail du produit anti-INSIG1 anticorps

Antigène: INSIG1 (Insulin Induced Gene 1 (INSIG1))

Épitope: AA 1-100

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp INSIG1 est non-conjugé

Application: Western Blotting (WB)

Fonction: Rabbit polyclonal antibody raised against synthetic peptide of INSIG1.

Specificité: This antibody is specific to Insig1 but not Insig2.

Réactivité croisée: Humain

Immunogène: A synthetic peptide corresponding to amino acids 1-100 of human INSIG1.

Information d'application

Indications d'application: Western Blot (2 μg/mL)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In PBS (30 % glycerol, 0.09 % sodium azide)

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Store at -20°C or -80°C.
Aliquot to avoid repeated freezing and thawing.

Références pour anticorps anti-INSIG1 (ABIN540703)

De Marinis, Martini, Trentalance, Pallottini: "Sex differences in hepatic regulation of cholesterol homeostasis." dans: The Journal of endocrinology, Vol. 198, Issue 3, pp. 635-43, (2008) (PubMed).

Gong, Lee, Lee, Goldstein, Brown, Ye: "Sterol-regulated ubiquitination and degradation of Insig-1 creates a convergent mechanism for feedback control of cholesterol synthesis and uptake." dans: Cell metabolism, Vol. 3, Issue 1, pp. 15-24, (2006) (PubMed).

Engelking, Liang, Hammer, Takaishi, Kuriyama, Evers, Li, Horton, Goldstein, Brown: "Schoenheimer effect explained--feedback regulation of cholesterol synthesis in mice mediated by Insig proteins." dans: The Journal of clinical investigation, Vol. 115, Issue 9, pp. 2489-98, (2005) (PubMed).

Détails sur INSIG1

Antigène: INSIG1 (Insulin Induced Gene 1 (INSIG1))

Autre désignation: INSIG1 (INSIG1 Produits)

Synonymes: anticorps cl-6, anticorps cl6, anticorps CL-6, anticorps CL6, anticorps fb55a03, anticorps fi35b10, anticorps wu:fb55a03, anticorps wu:fi35b10, anticorps zgc:55439, anticorps 1810013C12Rik, anticorps Insig-1, anticorps INSIG-1, anticorps insulin induced gene 1, anticorps insulin induced gene 1 L homeolog, anticorps INSIG1, anticorps insig1, anticorps insig1.L, anticorps Insig1

ID gène: 3638

Pathways: ER-Nucleus Signaling