LRP6 anticorps (pThr1479)

N° du produit ABIN540939

Détail du produit anti-LRP6 anticorps

Antigène: LRP6 (Low Density Lipoprotein Receptor-Related Protein 6 (LRP6))

Épitope: pThr1479

Reactivité: Humain, Souris, Rat, Boeuf (Vache)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LRP6 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP), Dot Blot (DB)

Fonction: Rabbit polyclonal antibody raised against synthetic phosphopeptide of LRP6.

Séquence: KGTYF

Specificité: This antibody recognizes ~180 KDa of human LRP6.

Réactivité croisée: Boeuf (Vache), Humain, Souris, Rat

Attributs du produit: Antibody Reactive Against Synthetic Peptide.

Immunogène: Synthetic phosphopeptide corresponding to residues surrounding T1479 of human LRP6.

Information d'application

Indications d'application: Western Blot (0.1-1 μg/mL)
ELISA (0.01-0.1 μg/mL)
Immunoprecipitation (2-5 μg/mL)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In TBS, pH 7.2 (BSA, 10 % Proclin300)

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Store at 4°C. For long term storage store at -20°C to -80°C.
Aliquot to avoid repeated freezing and thawing.

Références pour anticorps anti-LRP6 (ABIN540939)

Wang, Chi, Yuan, Zhou, Yin, Zhang, Peng: "Astragaloside IV inhibits the up-regulation of Wnt/?-catenin signaling in rats with unilateral ureteral obstruction." dans: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 33, Issue 5, pp. 1316-28, (2014) (PubMed).

Del Valle-Pérez, Arqués, Vinyoles, de Herreros, Duñach: "Coordinated action of CK1 isoforms in canonical Wnt signaling." dans: Molecular and cellular biology, Vol. 31, Issue 14, pp. 2877-88, (2011) (PubMed).

Casagolda, Del Valle-Pérez, Valls, Lugilde, Vinyoles, Casado-Vela, Solanas, Batlle, Reynolds, Casal, de Herreros, Duñach: "A p120-catenin-CK1epsilon complex regulates Wnt signaling." dans: Journal of cell science, Vol. 123, Issue Pt 15, pp. 2621-31, (2010) (PubMed).

Khan, Vijayakumar, de la Torre, Rotolo, Bafico: "Analysis of endogenous LRP6 function reveals a novel feedback mechanism by which Wnt negatively regulates its receptor." dans: Molecular and cellular biology, Vol. 27, Issue 20, pp. 7291-301, (2007) (PubMed).

Détails sur LRP6

Antigène: LRP6 (Low Density Lipoprotein Receptor-Related Protein 6 (LRP6))

Autre désignation: LRP6 (LRP6 Produits)

Synonymes: anticorps lrp6-A, anticorps Xlrp6, anticorps adcad2, anticorps lrp6, anticorps LRP6, anticorps ADCAD2, anticorps C030016K15Rik, anticorps Cd, anticorps Gw, anticorps LDL receptor related protein 6, anticorps LDL receptor related protein 6 L homeolog, anticorps LDL receptor related protein 6 S homeolog, anticorps low density lipoprotein receptor-related protein 6, anticorps low-density lipoprotein receptor-related protein 6, anticorps LRP6, anticorps lrp6.L, anticorps lrp6.S, anticorps lrp6, anticorps Lrp6, anticorps LOC590395

ID gène: 4040

Pathways: Signalisation WNT, Tube Formation