IRS1 anticorps (Internal Region)

N° du produit ABIN541257

Détail du produit anti-IRS1 anticorps

Antigène: IRS1 (Insulin Receptor Substrate 1 (IRS1))

Épitope: Internal Region

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IRS1 est non-conjugé

Application: Western Blotting (WB), Immunocytochemistry (ICC)

Fonction: Rabbit polyclonal antibody raised against synthetic peptide of IRS1.

Réactivité croisée: Humain, Souris

Immunogène: A synthetic peptide corresponding to internal region 16 amino acids of human IRS1.

Information d'application

Indications d'application: Western Blot (1-2 μg/mL)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In PBS (0.02 % sodium azide)

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

Références pour anticorps anti-IRS1 (ABIN541257)

Shamji, Nghiem, Schreiber: "Integration of growth factor and nutrient signaling: implications for cancer biology." dans: Molecular cell, Vol. 12, Issue 2, pp. 271-80, (2003) (PubMed).

Giovannone, Scaldaferri, Federici, Porzio, Lauro, Fusco, Sbraccia, Borboni, Lauro, Sesti: "Insulin receptor substrate (IRS) transduction system: distinct and overlapping signaling potential." dans: Diabetes/metabolism research and reviews, Vol. 16, Issue 6, pp. 434-41, (2001) (PubMed).

Ozes, Akca, Mayo, Gustin, Maehama, Dixon, Donner: "A phosphatidylinositol 3-kinase/Akt/mTOR pathway mediates and PTEN antagonizes tumor necrosis factor inhibition of insulin signaling through insulin receptor substrate-1." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 98, Issue 8, pp. 4640-5, (2001) (PubMed).

Détails sur IRS1

Antigène: IRS1 (Insulin Receptor Substrate 1 (IRS1))

Autre désignation: IRS1 (IRS1 Produits)

Synonymes: anticorps HIRS-1, anticorps G972R, anticorps IRS-1, anticorps IRS1IRM, anticorps irs1, anticorps irsu, anticorps IRS1, anticorps irs-1, anticorps irs1-a, anticorps insulin receptor substrate 1, anticorps insulin receptor substrate 2, anticorps insulin receptor substrate 1 S homeolog, anticorps IRS1, anticorps Irs1, anticorps irs2, anticorps irs1.S

ID gène: 3667

Pathways: Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Hormone Transport, Negative Regulation of Hormone Secretion, Response to Growth Hormone Stimulus, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process