UNC93B1 anticorps (N-Term)

N° du produit ABIN541343

Détail du produit anti-UNC93B1 anticorps

Antigène: UNC93B1 (Unc-93 Homolog B1 (UNC93B1))

Épitope: N-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UNC93B1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: Rabbit polyclonal antibody raised against synthetic peptide of UNC93B1.

Réactivité croisée: Humain, Souris, Rat

Immunogène: A synthetic peptide corresponding to N-terminus 19 amino acids of human UNC93B1.

Information d'application

Indications d'application: Western Blot (0.5-1 μg/mL)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In PBS (0.02 % sodium azide)

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

Références pour anticorps anti-UNC93B1 (ABIN541343)

Panchanathan, Liu, Choubey: "Expression of murine Unc93b1 is up-regulated by interferon and estrogen signaling: implications for sex bias in the development of autoimmunity." dans: International immunology, Vol. 25, Issue 9, pp. 521-9, (2013) (PubMed).

Brinkmann, Spooner, Hoebe, Beutler, Ploegh, Kim: "The interaction between the ER membrane protein UNC93B and TLR3, 7, and 9 is crucial for TLR signaling." dans: The Journal of cell biology, Vol. 177, Issue 2, pp. 265-75, (2007) (PubMed).

Tabeta, Hoebe, Janssen, Du, Georgel, Crozat, Mudd, Mann, Sovath, Goode, Shamel, Herskovits, Portnoy, Cooke, Tarantino, Wiltshire, Steinberg, Grinstein, Beutler: "The Unc93b1 mutation 3d disrupts exogenous antigen presentation and signaling via Toll-like receptors 3, 7 and 9." dans: Nature immunology, Vol. 7, Issue 2, pp. 156-64, (2006) (PubMed).

Liu, Dodds, Emilion, Mungall, Dunham, Beck, Wells, Charnock, Ganesan: "The human homologue of unc-93 maps to chromosome 6q27 - characterisation and analysis in sporadic epithelial ovarian cancer." dans: BMC genetics, Vol. 3, pp. 20, (2002) (PubMed).

Détails sur UNC93B1

Antigène: UNC93B1 (Unc-93 Homolog B1 (UNC93B1))

Autre désignation: UNC93B1 (UNC93B1 Produits)

Synonymes: anticorps UNC93, anticorps IIAE1, anticorps UNC93B, anticorps Unc-93B1, anticorps Unc93b, anticorps unc-93 homolog B1, TLR signaling regulator, anticorps unc-93 homolog B1 (C. elegans), anticorps UNC93B1, anticorps Unc93b1

ID gène: 81622

Pathways: Signalisation TLR, Activation of Innate immune Response, Toll-Like Receptors Cascades