DIABLO anticorps (AA 225-239)

N° du produit ABIN541409

Détail du produit anti-DIABLO anticorps

Antigène: DIABLO (Second Mitochondria-Derived Activator of Caspase (DIABLO))

Épitope: AA 225-239

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DIABLO est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: Rabbit polyclonal antibody raised against synthetic peptide of DIABLO.

Specificité: Human heart tissue lysate can be used as positive control and a 25 KDa band can be detected.

Réactivité croisée: Humain, Souris, Rat

Immunogène: A synthetic peptide corresponding to amino acids 225-239 of human DIABLO.

Information d'application

Indications d'application: Western Blot (0.5-1 μg/mL)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In PBS (0.02 % sodium azide)

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

Références pour anticorps anti-DIABLO (ABIN541409)

Du, Fang, Li, Li, Wang: "Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition." dans: Cell, Vol. 102, Issue 1, pp. 33-42, (2000) (PubMed).

Srinivasula, Datta, Fan, Fernandes-Alnemri, Huang, Alnemri: "Molecular determinants of the caspase-promoting activity of Smac/DIABLO and its role in the death receptor pathway." dans: The Journal of biological chemistry, Vol. 275, Issue 46, pp. 36152-7, (2000) (PubMed).

Chai, Du, Wu, Kyin, Wang, Shi: "Structural and biochemical basis of apoptotic activation by Smac/DIABLO." dans: Nature, Vol. 406, Issue 6798, pp. 855-62, (2000) (PubMed).

Détails sur DIABLO

Antigène: DIABLO (Second Mitochondria-Derived Activator of Caspase (DIABLO))

Autre désignation: DIABLO / SMAC (DIABLO Produits)

Synonymes: anticorps smac, anticorps smac3, anticorps diablo-s, anticorps 0610041G12Rik, anticorps 1700006L01Rik, anticorps AU040403, anticorps Smac, anticorps DFNA64, anticorps SMAC, anticorps DBO, anticorps XSmac, anticorps diablo, IAP-binding mitochondrial protein, anticorps diablo IAP-binding mitochondrial protein, anticorps diablo, IAP-binding mitochondrial protein L homeolog, anticorps diablo, anticorps Diablo, anticorps DIABLO, anticorps diablo.L

ID gène: 56616

Pathways: Apoptose, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity