BICD2
Reactivité: Humain
WB, IP
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
Western Blot (1-2 μg/mL) The optimal working dilution should be determined by the end user.
Restrictions
For Research Use only
Format
Liquid
Buffer
In PBS (0.02 % sodium azide)
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C,-20 °C
Stockage commentaire
Store at 4°C for three months. For long term storage store at -20°C. Aliquot to avoid repeated freezing and thawing.
Teuling, van Dis, Wulf, Haasdijk, Akhmanova, Hoogenraad, Jaarsma: "A novel mouse model with impaired dynein/dynactin function develops amyotrophic lateral sclerosis (ALS)-like features in motor neurons and improves lifespan in SOD1-ALS mice." dans: Human molecular genetics, Vol. 17, Issue 18, pp. 2849-62, (2008) (PubMed).
Holland, Milne, Garka, Johnson, Willis, Sims, Rauch, Bird, Virca: "Purification, cloning, and characterization of Nek8, a novel NIMA-related kinase, and its candidate substrate Bicd2." dans: The Journal of biological chemistry, Vol. 277, Issue 18, pp. 16229-40, (2002) (PubMed).
Hoogenraad, Akhmanova, Howell, Dortland, De Zeeuw, Willemsen, Visser, Grosveld, Galjart: "Mammalian Golgi-associated Bicaudal-D2 functions in the dynein-dynactin pathway by interacting with these complexes." dans: The EMBO journal, Vol. 20, Issue 15, pp. 4041-54, (2001) (PubMed).