ASK1 anticorps (Ser966)

N° du produit ABIN543242

Détail du produit anti-ASK1 anticorps

Antigène: ASK1 (MAP3K5) (Mitogen-Activated Protein Kinase Kinase Kinase 5 (MAP3K5))

Épitope: Ser966

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ASK1 est non-conjugé

Application: Western Blotting (WB)

Fonction: Rabbit polyclonal antibody raised against synthetic peptide of MAP3K5.

Réactivité croisée: Humain

Immunogène: A synthetic peptide (conjugated with KLH) corresponding to residues surrounding S966 of human MAP3K5.

Information d'application

Indications d'application: Western Blot (1:1000)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In PBS (0.09 % sodium azide)

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

Références pour anticorps anti-ASK1 (ABIN543242)

Noguchi, Ishii, Fukutomi, Naguro, Matsuzawa, Takeda, Ichijo: "Requirement of reactive oxygen species-dependent activation of ASK1-p38 MAPK pathway for extracellular ATP-induced apoptosis in macrophage." dans: The Journal of biological chemistry, Vol. 283, Issue 12, pp. 7657-65, (2008) (PubMed).

Li, Luo, Yu, Lin, Luo, Zhang, He, Kim, Kim, Tang, Min: "SENP1 mediates TNF-induced desumoylation and cytoplasmic translocation of HIPK1 to enhance ASK1-dependent apoptosis." dans: Cell death and differentiation, Vol. 15, Issue 4, pp. 739-50, (2008) (PubMed).

Min, Lin, Tang, Yu, Zhang, Wan, Luhn, Fu, Chen: "AIP1 recruits phosphatase PP2A to ASK1 in tumor necrosis factor-induced ASK1-JNK activation." dans: Circulation research, Vol. 102, Issue 7, pp. 840-8, (2008) (PubMed).

Détails sur ASK1

Antigène: ASK1 (MAP3K5) (Mitogen-Activated Protein Kinase Kinase Kinase 5 (MAP3K5))

Autre désignation: MEKK5 / ASK1 (MAP3K5 Produits)

Synonymes: anticorps ASK1, anticorps MAPKKK5, anticorps MEKK5, anticorps mitogen-activated protein kinase kinase kinase 5, anticorps MUD21.11, anticorps MUD21_11, anticorps 7420452D20Rik, anticorps ASK, anticorps Mekk5, anticorps Ask1, anticorps RGD1306565, anticorps mitogen-activated protein kinase kinase kinase 5, anticorps MAP3K5, anticorps MAPKKK5, anticorps Map3k5, anticorps map3k5

ID gène: 4217

Pathways: Signalisation MAPK, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response