Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:50-100) Western Blot (1:1000) The optimal working dilution should be determined by the end user.
Restrictions
For Research Use only
Format
Liquid
Buffer
In PBS (0.09 % sodium azide)
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C,-20 °C
Stockage commentaire
Store at 4°C. For long term storage store at -20°C. Aliquot to avoid repeated freezing and thawing.
Grönholm, Vossebein, Carlson, Kuja-Panula, Teesalu, Alfthan, Vaheri, Rauvala, Herberg, Taskén, Carpén: "Merlin links to the cAMP neuronal signaling pathway by anchoring the RIbeta subunit of protein kinase A." dans: The Journal of biological chemistry, Vol. 278, Issue 42, pp. 41167-72, (2003) (PubMed).
Stergiopoulos, Stratakis: "Human tumors associated with Carney complex and germline PRKAR1A mutations: a protein kinase A disease!" dans: FEBS letters, Vol. 546, Issue 1, pp. 59-64, (2003) (PubMed).
Bertherat, Groussin, Sandrini, Matyakhina, Bei, Stergiopoulos, Papageorgiou, Bourdeau, Kirschner, Vincent-Dejean, Perlemoine, Gicquel, Bertagna, Stratakis: "Molecular and functional analysis of PRKAR1A and its locus (17q22-24) in sporadic adrenocortical tumors: 17q losses, somatic mutations, and protein kinase A expression and activity." dans: Cancer research, Vol. 63, Issue 17, pp. 5308-19, (2003) (PubMed).
Antigène
PRKAR1A
(Protein Kinase, CAMP-Dependent, Regulatory, Type I, alpha (Tissue Specific Extinguisher 1) (PRKAR1A))