LYN anticorps (N-Term)

N° du produit ABIN544389

Détail du produit anti-LYN anticorps

Antigène: LYN (V-Yes-1 Yamaguchi Sarcoma Viral Related Oncogene Homolog (LYN))

Épitope: N-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LYN est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Fonction: Rabbit polyclonal antibody raised against synthetic peptide of LYN.

Réactivité croisée: Humain, Souris

Immunogène: A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human LYN.

Information d'application

Indications d'application: Flow Cytometry (1:10-50)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:50-100)
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In PBS (0.09 % sodium azide)

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

Références pour anticorps anti-LYN (ABIN544389)

Baran, Tridandapani, Helgason, Humphries, Krystal, Marsh: "The inositol 5'-phosphatase SHIP-1 and the Src kinase Lyn negatively regulate macrophage colony-stimulating factor-induced Akt activity." dans: The Journal of biological chemistry, Vol. 278, Issue 40, pp. 38628-36, (2003) (PubMed).

Donato, Wu, Stapley, Gallick, Lin, Arlinghaus, Talpaz: "BCR-ABL independence and LYN kinase overexpression in chronic myelogenous leukemia cells selected for resistance to STI571." dans: Blood, Vol. 101, Issue 2, pp. 690-8, (2003) (PubMed).

Santini, Scappini, Grossi, Gozzini, Bonsi, Pagliai, Rossi Ferrini, Bagnara: "Lyn kinase is activated following thrombopoietin stimulation of the megakaryocytic cell line B1647." dans: Haematologica, Vol. 87, Issue 12, pp. 1242-7, (2002) (PubMed).

Détails sur LYN

Antigène: LYN (V-Yes-1 Yamaguchi Sarcoma Viral Related Oncogene Homolog (LYN))

Autre désignation: LYN (LYN Produits)

Synonymes: anticorps JTK8, anticorps p53Lyn, anticorps p56Lyn, anticorps lyn, anticorps LYN, anticorps AA407514, anticorps Hck-2, anticorps jtk8, anticorps lyn-A, anticorps CH73-38P6.3, anticorps zgc:92124, anticorps LYN proto-oncogene, Src family tyrosine kinase, anticorps v-yes-1 Yamaguchi sarcoma viral related oncogene homolog, anticorps tyrosine-protein kinase Lyn, anticorps LYN proto-oncogene, Src family tyrosine kinase L homeolog, anticorps LYN, anticorps lyn, anticorps Lyn, anticorps LOC100593961, anticorps lyn.L

ID gène: 4067

Pathways: Fc-epsilon Receptor Signaling Pathway, Hormone Transport, Response to Growth Hormone Stimulus, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling, Integrin Complex, BCR Signaling