GCK anticorps (C-Term)

N° du produit ABIN544490

Détail du produit anti-GCK anticorps

Antigène: GCK (Glucokinase (Hexokinase 4) (GCK))

Épitope: C-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GCK est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: Rabbit polyclonal antibody raised against synthetic peptide of GCK.

Réactivité croisée: Humain, Souris

Immunogène: A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human GCK.

Information d'application

Indications d'application: Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:50-100)
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In PBS (0.09 % sodium azide)

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

Références pour anticorps anti-GCK (ABIN544490)

Gloyn, Noordam, Willemsen, Ellard, Lam, Campbell, Midgley, Shiota, Buettger, Magnuson, Matschinsky, Hattersley: "Insights into the biochemical and genetic basis of glucokinase activation from naturally occurring hypoglycemia mutations." dans: Diabetes, Vol. 52, Issue 9, pp. 2433-40, (2003) (PubMed).

Pruhova, Ek, Lebl, Sumnik, Saudek, Andel, Pedersen, Hansen: "Genetic epidemiology of MODY in the Czech republic: new mutations in the MODY genes HNF-4alpha, GCK and HNF-1alpha." dans: Diabetologia, Vol. 46, Issue 2, pp. 291-5, (2003) (PubMed).

Rizzo, Magnuson, Drain, Piston: "A functional link between glucokinase binding to insulin granules and conformational alterations in response to glucose and insulin." dans: The Journal of biological chemistry, Vol. 277, Issue 37, pp. 34168-75, (2002) (PubMed).

Détails sur GCK

Antigène: GCK (Glucokinase (Hexokinase 4) (GCK))

Autre désignation: Glucokinase / Hexokinase-4 (GCK Produits)

Synonymes: anticorps FGQTL3, anticorps GK, anticorps GLK, anticorps HHF3, anticorps HK4, anticorps HKIV, anticorps HXKP, anticorps LGLK, anticorps MODY2, anticorps Gk, anticorps Gls006, anticorps GCK, anticorps BA4487, anticorps glk, anticorps hk4, anticorps hhf3, anticorps hkiv, anticorps hxkp, anticorps gck-A, anticorps mody2, anticorps glucokinase, anticorps GLUKA, anticorps RNGK2, anticorps glucokinase, anticorps glucokinase (hexokinase 4) L homeolog, anticorps glucokinase (hexokinase 4), anticorps GCK, anticorps Gck, anticorps glcK, anticorps Bphyt_1025, anticorps Halhy_6548, anticorps gk, anticorps gck.L, anticorps gck

ID gène: 2645

Pathways: Signalisation MAPK, Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis, Cellular Glucan Metabolic Process, Regulation of Carbohydrate Metabolic Process