Integrin beta 4 anticorps (pTyr1494)

N° du produit ABIN548462

Détail du produit anti-Integrin beta 4 anticorps

Antigène: Integrin beta 4 (ITGB4)

Épitope: pTyr1494

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Integrin beta 4 est non-conjugé

Application: Western Blotting (WB), ELISA

Fonction: Rabbit polyclonal antibody raised against synthetic phosphopeptide of ITGB4.

Specificité: This peptide sequence is found in all three integrin-b4 isoforms and is highly conserved in rat and mouse integrin-b4.

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Antibody Reactive Against Synthetic Peptide.

Immunogène: Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding Y1494 of human ITGB4.

Information d'application

Indications d'application: ELISA (1:4000)
Western Blot (1:2000)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In PBS (50 % glycerol, 1 mg/mL BSA, 0.05 % sodium azide)

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C.
Aliquot to avoid repeated freezing and thawing.

Références pour anticorps anti-Integrin beta 4 (ABIN548462)

Kim, Huang, Cheepala, Huang, Chung: "Curcumin inhibition of integrin (alpha6beta4)-dependent breast cancer cell motility and invasion." dans: Cancer prevention research (Philadelphia, Pa.), Vol. 1, Issue 5, pp. 385-91, (2009) (PubMed).

Shaw: "Identification of insulin receptor substrate 1 (IRS-1) and IRS-2 as signaling intermediates in the alpha6beta4 integrin-dependent activation of phosphoinositide 3-OH kinase and promotion of invasion." dans: Molecular and cellular biology, Vol. 21, Issue 15, pp. 5082-93, (2001) (PubMed).

Dans, Gagnoux-Palacios, Blaikie, Klein, Mariotti, Giancotti: "Tyrosine phosphorylation of the beta 4 integrin cytoplasmic domain mediates Shc signaling to extracellular signal-regulated kinase and antagonizes formation of hemidesmosomes." dans: The Journal of biological chemistry, Vol. 276, Issue 2, pp. 1494-502, (2001) (PubMed).

Détails sur Integrin beta 4

Antigène: Integrin beta 4 (ITGB4)

Autre désignation: CD104 (ITGB4 Produits)

Synonymes: anticorps AA407042, anticorps C230078O20, anticorps CD104, anticorps integrin subunit beta 4, anticorps integrin beta 4, anticorps ITGB4, anticorps Itgb4

ID gène: 3691

Pathways: Integrin Complex