NFAT1 anticorps (pSer330)

N° du produit ABIN548643

Détail du produit anti-NFAT1 anticorps

Antigène: NFAT1 (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 2 (NFAT1))

Épitope: pSer330

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NFAT1 est non-conjugé

Application: ELISA, Dot Blot (DB)

Fonction: Rabbit polyclonal antibody raised against synthetic phosphopeptide of NFATC2.

Réactivité croisée: Humain

Immunogène: Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding S330 of human NFATC2.

Information d'application

Indications d'application: ELISA (1:1000)
Dot Blot (1:500)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In PBS (0.09 % sodium azide)

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

Références pour anticorps anti-NFAT1 (ABIN548643)

Dong, Patino-Lopez, Candotti, Shaw: "Structure-function analysis of the WIP role in T cell receptor-stimulated NFAT activation: evidence that WIP-WASP dissociation is not required and that the WIP NH2 terminus is inhibitory." dans: The Journal of biological chemistry, Vol. 282, Issue 41, pp. 30303-10, (2007) (PubMed).

Gibson, Hedgcock, Aufiero, Wilson, Hafner, Tsokos, Wong: "Induction of the CTLA-4 gene in human lymphocytes is dependent on NFAT binding the proximal promoter." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 179, Issue 6, pp. 3831-40, (2007) (PubMed).

Golks, Tran, Goetschy, Guerini: "Requirement for O-linked N-acetylglucosaminyltransferase in lymphocytes activation." dans: The EMBO journal, Vol. 26, Issue 20, pp. 4368-79, (2007) (PubMed).

Détails sur NFAT1

Antigène: NFAT1 (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 2 (NFAT1))

Autre désignation: NFATC2 (NFAT1 Produits)

Synonymes: anticorps NFATC2, anticorps AI607462, anticorps NF-ATc2, anticorps NFAT1, anticorps NFAT1-D, anticorps Nfatp, anticorps NFATP, anticorps nuclear factor of activated T-cells 2, anticorps nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2, anticorps NFATC2, anticorps nfatc2, anticorps Nfatc2

ID gène: 4773

Pathways: Signalisation RTK, Signalisation WNT, Fc-epsilon Receptor Signaling Pathway, VEGF Signaling, BCR Signaling