Western Blot (1:1000) The optimal working dilution should be determined by the end user.
Restrictions
For Research Use only
Format
Liquid
Buffer
In 10 mM HEPES, 150 mM NaCl, pH 7.5 (50 % glycerol, 10 % BSA)
Stock
-20 °C
Stockage commentaire
Store at -20°C. Aliquot to avoid repeated freezing and thawing.
Cameron, Abe, Malik, Che, Yang: "Differential role of MEK5alpha and MEK5beta in BMK1/ERK5 activation." dans: The Journal of biological chemistry, Vol. 279, Issue 2, pp. 1506-12, (2004) (PubMed).
Mehta, Jenkins, McCarthy, Thilak, Robson, Neal, Leung: "MEK5 overexpression is associated with metastatic prostate cancer, and stimulates proliferation, MMP-9 expression and invasion." dans: Oncogene, Vol. 22, Issue 9, pp. 1381-9, (2003) (PubMed).
Chao, Hayashi, Tapping, Kato, Lee: "MEKK3 directly regulates MEK5 activity as part of the big mitogen-activated protein kinase 1 (BMK1) signaling pathway." dans: The Journal of biological chemistry, Vol. 274, Issue 51, pp. 36035-8, (2000) (PubMed).
Antigène
MAP2K5
(Mitogen-Activated Protein Kinase Kinase 5 (MAP2K5))