ASK1 anticorps (pSer83)

N° du produit ABIN550447

Détail du produit anti-ASK1 anticorps

Antigène: ASK1 (MAP3K5) (Mitogen-Activated Protein Kinase Kinase Kinase 5 (MAP3K5))

Épitope: pSer83

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ASK1 est non-conjugé

Application: Western Blotting (WB), ELISA

Fonction: Rabbit polyclonal antibody raised against synthetic phosphpeptide of MAP3K5.

Specificité: This phospho specific polyclonal antibody reacts human pS83 ASK1.

Réactivité croisée: Humain, Souris

Attributs du produit: Antibody Reactive Against Synthetic Peptide.

Immunogène: Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding S83 of human MAP3K5.

Information d'application

Indications d'application: ELISA (1:5000-1:10000)
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 20 mM KH₂PO₄, 150 mM NaCl, pH 7.2 (0.01 % sodium azide)

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

Références pour anticorps anti-ASK1 (ABIN550447)

Zou, Tsutsui, Ray, Blomquist, Ichijo, Ucker, Kiyokawa: "The cell cycle-regulatory CDC25A phosphatase inhibits apoptosis signal-regulating kinase 1." dans: Molecular and cellular biology, Vol. 21, Issue 14, pp. 4818-28, (2001) (PubMed).

Matsuzawa, Ichijo: "Molecular mechanisms of the decision between life and death: regulation of apoptosis by apoptosis signal-regulating kinase 1." dans: Journal of biochemistry, Vol. 130, Issue 1, pp. 1-8, (2001) (PubMed).

Morita, Saitoh, Tobiume, Matsuura, Enomoto, Nishitoh, Ichijo: "Negative feedback regulation of ASK1 by protein phosphatase 5 (PP5) in response to oxidative stress." dans: The EMBO journal, Vol. 20, Issue 21, pp. 6028-36, (2001) (PubMed).

Détails sur ASK1

Antigène: ASK1 (MAP3K5) (Mitogen-Activated Protein Kinase Kinase Kinase 5 (MAP3K5))

Autre désignation: MEKK5 / ASK1 (MAP3K5 Produits)

Synonymes: anticorps ASK1, anticorps MAPKKK5, anticorps MEKK5, anticorps mitogen-activated protein kinase kinase kinase 5, anticorps MUD21.11, anticorps MUD21_11, anticorps 7420452D20Rik, anticorps ASK, anticorps Mekk5, anticorps Ask1, anticorps RGD1306565, anticorps mitogen-activated protein kinase kinase kinase 5, anticorps MAP3K5, anticorps MAPKKK5, anticorps Map3k5, anticorps map3k5

ID gène: 4217

Pathways: Signalisation MAPK, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response