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Calpain 6 anticorps (Middle Region)

CAPN6 Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN5514668
  • Antigène Voir toutes Calpain 6 (CAPN6) Anticorps
    Calpain 6 (CAPN6)
    Épitope
    • 7
    • 7
    • 7
    • 6
    • 5
    • 2
    • 1
    • 1
    Middle Region
    Reactivité
    • 32
    • 6
    • 3
    Humain
    Hôte
    • 30
    • 3
    Lapin
    Clonalité
    • 30
    • 3
    Polyclonal
    Conjugué
    • 13
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Calpain 6 est non-conjugé
    Application
    • 23
    • 20
    • 17
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB)
    Séquence
    TIPNHKEQEW DPQKTEKYAG IFHFRFWHFG EWTEVVIDDL LPTINGDLVF
    Purification
    Affinity purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the middle region of human CAPN6
    Top Product
    Discover our top product CAPN6 Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    Calpain 6 (CAPN6)
    Autre désignation
    CAPN6 (CAPN6 Produits)
    Synonymes
    anticorps CAPN6, anticorps CANPX, anticorps CAPNX, anticorps CalpM, anticorps DJ914P14.1, anticorps calpain 6, anticorps CAPN6, anticorps Capn6
    Sujet
    Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The protein encoded by this gene is highly expressed in the placenta. Its C-terminal region lacks any homology to the calmodulin-like domain of other calpains. The protein lacks critical active site residues and thus is suggested to be proteolytically inactive. The protein may play a role in tumor formation by inhibiting apoptosis and promoting angiogenesis.

    Alias Symbols: CANPX, CAPNX, CalpM, DJ914P14.1

    Protein Size: 641
    ID gène
    827
    NCBI Accession
    NM_014289, NP_055104
    UniProt
    Q9Y6Q1
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