IBTK anticorps (C-Term)

N° du produit ABIN5514895

Détail du produit anti-IBTK anticorps

Antigène: IBTK (Inhibitor of Bruton Agammaglobulinemia Tyrosine Kinase (IBTK))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IBTK est non-conjugé

Application: Western Blotting (WB)

Séquence: GDIFLKEEIN MEQNHSETMF KKAKTKAKKK PRKRSDSSGG YNLSDIIQSP

Attributs du produit: This is a rabbit polyclonal antibody against IBTK. It was validated on Western Blot.

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Human IBTK

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur IBTK

Antigène: IBTK (Inhibitor of Bruton Agammaglobulinemia Tyrosine Kinase (IBTK))

Autre désignation: IBTK (IBTK Produits)

Synonymes: anticorps IBTK, anticorps fi40c08, anticorps wu:fi40c08, anticorps DKFZp468J085, anticorps BTBD26, anticorps BTKI, anticorps RP1-93K22.1, anticorps 5430411K16Rik, anticorps AA409502, anticorps mKIAA1417, anticorps inhibitor of Bruton tyrosine kinase, anticorps inhibitor of Bruton agammaglobulinemia tyrosine kinase, anticorps inhibitor of Bruton tyrosine kinase L homeolog, anticorps IBTK, anticorps ibtk, anticorps Ibtk, anticorps ibtk.L

Sujet: Bruton tyrosine kinase (BTK) is a protein tyrosine kinase that is expressed in B cells, macrophages, and neutrophils. The protein encoded by this gene binds to BTK and downregulates BTK's kinase activity. In addition, the encoded protein disrupts BTK-mediated calcium mobilization and negatively regulates the activation of nuclear factor-kappa-B-driven transcription. This gene has a pseudogene on chromosome 18. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Alias Symbols: IBTK, BTKI, KIAA1417,

Protein Interaction Partner: IGSF8, CD81, LAMTOR3, ITK, BTK, AKT1, PRKD1, PRKCG, PRKCE, PRKCD, PRKCB, PRKCA, PLCG1, CUL3, PPP1CA, UBC, RGS2,

Protein Size: 1353

ID gène: 25998

NCBI Accession: NP_056340

UniProt: Q9P2D0