ASIP anticorps (Middle Region)

N° du produit ABIN5515388

Détail du produit anti-ASIP anticorps

Antigène: ASIP (Agouti Signaling Protein (ASIP))

Épitope: Middle Region

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ASIP est non-conjugé

Application: Western Blotting (WB)

Séquence: CFFTANSHLP PEEKLRDDRS LRSNSSVNLL DVPSVSIVAL NKKSKQIGRK

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human ASIP

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur ASIP

Antigène: ASIP (Agouti Signaling Protein (ASIP))

Autre désignation: ASIP (ASIP Produits)

Synonymes: anticorps AGSW, anticorps AGTI, anticorps AGTIL, anticorps ASP, anticorps SHEP9, anticorps ASIP, anticorps AA960621, anticorps AI256638, anticorps D8Ertd580e, anticorps PAR-3, anticorps Par3, anticorps Pard3a, anticorps agouti signaling protein, anticorps par-3 family cell polarity regulator, anticorps ASIP, anticorps Asip, anticorps asip, anticorps Pard3

Sujet: In mice, the agouti gene encodes a paracrine signaling molecule that causes hair follicle melanocytes to synthesize pheomelanin, a yellow pigment, instead of the black or brown pigment, eumelanin. Pleiotropic effects of constitutive expression of the mouse gene include adult-onset obesity, increased tumor susceptibility, and premature infertility. This gene is highly similar to the mouse gene and encodes a secreted protein that may (1) affect the quality of hair pigmentation, (2) act as a pharmacological antagonist of alpha-melanocyte-stimulating hormone, (3) play a role in neuroendocrine aspects of melanocortin action, and (4) have a functional role in regulating lipid metabolism in adipocytes.

Alias Symbols: ASP, AGSW, AGTI, AGTIL, SHEP9

Protein Size: 132

ID gène: 434

NCBI Accession: NM_001672, NP_001663

UniProt: P42127

Pathways: Cell-Cell Junction Organization, Feeding Behaviour