GNB3 anticorps (C-Term)

N° du produit ABIN5515493

Détail du produit anti-GNB3 anticorps

Antigène: GNB3 (Guanine Nucleotide Binding Protein (G Protein), beta Polypeptide 3 (GNB3))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GNB3 est non-conjugé

Application: Western Blotting (WB)

Séquence: SIICGITSVA FSLSGRLLFA GYDDFNCNVW DSMKSERVGI LSGHDNRVSC

Attributs du produit: This is a rabbit polyclonal antibody against GNB3. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Human GNB3

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur GNB3

Antigène: GNB3 (Guanine Nucleotide Binding Protein (G Protein), beta Polypeptide 3 (GNB3))

Autre désignation: GNB3 (GNB3 Produits)

Synonymes: anticorps Gnb-3, anticorps MGC68913, anticorps MGC130764, anticorps gnb3, anticorps zgc:73058, anticorps zgc:77780, anticorps wu:fk54b04, anticorps gnb3l, anticorps zgc:92641, anticorps G protein subunit beta 3, anticorps guanine nucleotide binding protein (G protein), beta 3, anticorps guanine nucleotide binding protein (G protein), beta polypeptide 3 S homeolog, anticorps guanine nucleotide binding protein (G protein), beta polypeptide 3b, anticorps guanine nucleotide binding protein (G protein), beta polypeptide 3a, anticorps GNB3, anticorps Gnb3, anticorps gnb3.S, anticorps gnb3b, anticorps gnb3a

Sujet: Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. A single-nucleotide polymorphism (C825T) in this gene is associated with essential hypertension and obesity. This polymorphism is also associated with the occurrence of the splice variant GNB3-s, which appears to have increased activity. GNB3-s is an example of alternative splicing caused by a nucleotide change outside of the splice donor and acceptor sites. Additional splice variants may exist for this gene, but they have not been fully described.

Alias Symbols: GNB3,

Protein Interaction Partner: UBC, MTOR, GNG8, GNG12, GNG2, GNG10, GNG5, GNAQ, GNAI3, GNA12, RASD2, PDCL, GNG13, RGS6, GNGT2, GNG11, GNG7, GNG4, GNG3, TGFBR1, git11,

Protein Size: 340

ID gène: 2784

NCBI Accession: NP_002066

UniProt: P16520

Pathways: Peptide Hormone Metabolism, Myometrial Relaxation and Contraction