MED17 anticorps (Middle Region)
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- Antigène Voir toutes MED17 Anticorps
- MED17 (Mediator Complex Subunit 17 (MED17))
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Épitope
- Middle Region
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp MED17 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- SAYIKVSIQK QAPDIGDLGT VNLFKRPLPK SKPGSPHWQT KLEAAQNVLL
- Attributs du produit
- This is a rabbit polyclonal antibody against MED17. It was validated on Western Blot.
- Purification
- Affinity purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of Human MED17
- Top Product
- Discover our top product MED17 Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- MED17 (Mediator Complex Subunit 17 (MED17))
- Autre désignation
- MED17 (MED17 Produits)
- Synonymes
- anticorps crsp6, anticorps CRSP6, anticorps CRSP77, anticorps DRIP80, anticorps TRAP80, anticorps 77kDa, anticorps C330002H14Rik, anticorps Crsp6, anticorps Trap80, anticorps mediator of RNA polymerase II transcription subunit 17, anticorps mediator complex subunit 17, anticorps mediator complex subunit 17 L homeolog, anticorps AOR_1_2446154, anticorps VDBG_01663, anticorps med17, anticorps med17.L, anticorps MED17, anticorps Med17
- Sujet
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The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors.
Alias Symbols: MED17, ARC77, CRSP6, DRIP77, DRIP80, TRAP80,
Protein Interaction Partner: UBC, BRCA1, CDK19, CDK8, MED26, POLR2C, ESR2, MED19, FBXW7, EPAS1, TFIP11, MED24, MED21, MED14, MED11, MED28, WDR33, CPSF2, UBD, BCL6, SMARCA4, SUZ12, MED10, CTDP1, SREBF1, MED25, MED15, TRA, MED1, OBFC1, MED18, ZC3H13, MED12, QKI, TRIP4, TADA2A, SUPT7L,
Protein Size: 651 - ID gène
- 9440
- NCBI Accession
- NP_004259
- UniProt
- Q9NVC6
- Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway, Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha
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