CISH anticorps (Middle Region)
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- Antigène Voir toutes CISH Anticorps
- CISH (Cytokine Inducible SH2-Containing Protein (CISH))
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Épitope
- Middle Region
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp CISH est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- RILAFPDVVS LVQHYVASCT ADTRSDSPDP APTPALPMPK EDAPSDPALP
- Purification
- Affinity purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human CISH
- Top Product
- Discover our top product CISH Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- CISH (Cytokine Inducible SH2-Containing Protein (CISH))
- Autre désignation
- CISH (CISH Produits)
- Synonymes
- anticorps CISH, anticorps cis, anticorps cish.a, anticorps ptk9l, anticorps twf1l, anticorps wu:fk57g04, anticorps zgc:154062, anticorps zgc:91817, anticorps g18, anticorps socs, anticorps cis-1, anticorps cish, anticorps BACTS2, anticorps CIS, anticorps CIS-1, anticorps G18, anticorps SOCS, anticorps AI385595, anticorps CIS1, anticorps Cis, anticorps F17, anticorps F23, anticorps cytokine inducible SH2 containing protein, anticorps cytokine inducible SH2-containing protein, anticorps CISH, anticorps cish, anticorps Cish
- Sujet
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The protein encoded by this gene contains a SH2 domain and a SOCS box domain. The protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI), protein family. CIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by IL2, IL3, GM-CSF and EPO in hematopoietic cells. Proteasome-mediated degradation of this protein has been shown to be involved in the inactivation of the erythropoietin receptor. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: CIS, G18, SOCS, CIS-1, BACTS2
Protein Size: 275 - ID gène
- 1154
- NCBI Accession
- NM_013324, NP_037456
- UniProt
- Q9NSE2
- Pathways
- Signalistation JAK/STAT, Response to Growth Hormone Stimulus
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