PDE6A anticorps (Middle Region)
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- Antigène Voir toutes PDE6A Anticorps
- PDE6A (phosphodiesterase 6A, CGMP-Specific, Rod, alpha (PDE6A))
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Épitope
- Middle Region
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp PDE6A est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- YTVRAFLNCD RYSVGLLDMT KQKEFFDVWP VLMGEVPPYS GPRTPDGREI
- Purification
- Affinity purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human PDE6A
- Top Product
- Discover our top product PDE6A Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- PDE6A (phosphodiesterase 6A, CGMP-Specific, Rod, alpha (PDE6A))
- Autre désignation
- PDE6A (PDE6A Produits)
- Synonymes
- anticorps si:bz1d10.3, anticorps si:rp71-1d10.3, anticorps CGPR-A, anticorps PDEA, anticorps RP43, anticorps Pdea, anticorps nmf282, anticorps phosphodiesterase 6A, cGMP-specific, rod, alpha, anticorps phosphodiesterase 6A, anticorps pde6a, anticorps PDE6A, anticorps Pde6a
- Sujet
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This gene encodes the cyclic-GMP (cGMP)-specific phosphodiesterase 6A alpha subunit, expressed in cells of the retinal rod outer segment. The phosphodiesterase 6 holoenzyme is a heterotrimer composed of an alpha, beta, and two gamma subunits. cGMP is an important regulator of rod cell membrane current, and its dynamic concentration is established by phosphodiesterase 6A cGMP hydrolysis and guanylate cyclase cGMP synthesis. The protein is a subunit of a key phototransduction enzyme and participates in processes of transmission and amplification of the visual signal. Mutations in this gene have been identified as one cause of autosomal recessive retinitis pigmentosa.
Alias Symbols: PDEA, RP43, CGPR-A
Protein Size: 167 - ID gène
- 5145
- NCBI Accession
- NM_000440, NP_000431
- UniProt
- P16499
- Pathways
- Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction
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