USP19 anticorps (Middle Region)

N° du produit ABIN5516193

Détail du produit anti-USP19 anticorps

Antigène: USP19 (Ubiquitin Specific Peptidase 19 (USP19))

Épitope: Middle Region

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp USP19 est non-conjugé

Application: Western Blotting (WB)

Séquence: SQFTGYAQHD AQEFMAFLLD GLHEDLNRIQ NKPYTETVDS DGRPDEVVAE

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human USP19

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur USP19

Antigène: USP19 (Ubiquitin Specific Peptidase 19 (USP19))

Autre désignation: USP19 (USP19 Produits)

Synonymes: anticorps wu:fc26a05, anticorps si:dkey-32e6.9, anticorps USP19, anticorps MGC145127, anticorps ZMYND9, anticorps 8430421I07Rik, anticorps AI047774, anticorps Zmynd9, anticorps ubiquitin specific peptidase 19, anticorps universal stress protein, anticorps ubiquitin carboxyl-terminal hydrolase 19, anticorps usp19, anticorps USP19, anticorps RR_RS18085, anticorps PTRG_09611, anticorps Usp19

Sujet: Deubiquitinating enzyme that regulates the degradation of various proteins. Deubiquitinates and prevents proteasomal degradation of RNF123 which in turn stimulates CDKN1B ubiquitin-dependent degradation thereby playing a role in cell proliferation. Involved in decreased protein synthesis in atrophying skeletal muscle. Modulates transcription of major myofibrillar proteins. Also involved in turnover of endoplasmic-reticulum-associated degradation (ERAD) substrates. Regulates the stability of BIRC2/c-IAP1 and BIRC3/c-IAP2 by preventing their ubiquitination. Required for cells to mount an appropriate response to hypoxia and rescues HIF1A from degradation in a non-catalytic manner. Plays an important role in 17 beta-estradiol (E2)-inhibited myogenesis. Decreases the levels of ubiquitinated proteins during skeletal muscle formation and acts to repress myogenesis. Exhibits a preference towards 'Lys-63'-linked Ubiquitin chains.

Alias Symbols: ZMYND9

Protein Size: 1419

ID gène: 10869

NCBI Accession: NM_001199160, NP_001186089