CDK2AP1 anticorps (Middle Region)

N° du produit ABIN5516286

Détail du produit anti-CDK2AP1 anticorps

Antigène: CDK2AP1 (Cyclin-Dependent Kinase 2 Associated Protein 1 (CDK2AP1))

Épitope: Middle Region

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CDK2AP1 est non-conjugé

Application: Western Blotting (WB)

Séquence: SPSTSMATSS QYRQLLSDYG PPSLGYTQGT GNSQVPQSKY AELLAIIEEL

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human CDK2AP1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur CDK2AP1

Antigène: CDK2AP1 (Cyclin-Dependent Kinase 2 Associated Protein 1 (CDK2AP1))

Autre désignation: CDK2AP1 (CDK2AP1 Produits)

Synonymes: anticorps MGC64532, anticorps doc1, anticorps st19, anticorps doc-1, anticorps dorc1, anticorps p12doc-1, anticorps Apc10, anticorps Cdkap1, anticorps DORC1, anticorps Doc1, anticorps ST19, anticorps p12, anticorps DOC1, anticorps p12DOC-1, anticorps cyclin-dependent kinase 2 associated protein 1 S homeolog, anticorps cyclin dependent kinase 2 associated protein 1, anticorps cyclin dependent kinase 2 associated protein 1 pseudogene, anticorps cyclin-dependent kinase 2 associated protein 1, anticorps CDK2 (cyclin-dependent kinase 2)-associated protein 1, anticorps cdk2ap1.S, anticorps CDK2AP1, anticorps LOC475806, anticorps cdk2ap1, anticorps Cdk2ap1

Sujet: The protein encoded by this gene is a cyclin-dependent kinase 2 (CDK2) -associated protein which is thought to negatively regulate CDK2 activity by sequestering monomeric CDK2, and targeting CDK2 for proteolysis. This protein was found to also interact with DNA polymerase alpha/primase and mediate the phosphorylation of the large p180 subunit, which suggests a regulatory role in DNA replication during the S-phase of the cell cycle. This protein also forms a core subunit of the nucleosome remodeling and histone deacetylation (NURD) complex that epigenetically regulates embryonic stem cell differentiation. This gene thus plays a role in both cell-cycle and epigenetic regulation. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Alias Symbols: DOC1, ST19, DORC1, doc-1, p12DOC-1

Protein Size: 115

ID gène: 8099

NCBI Accession: NM_001270433, NP_001257362

UniProt: O14519