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CBX7 anticorps (C-Term)

CBX7 Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN5516358
  • Antigène Voir toutes CBX7 Anticorps
    CBX7 (Chromobox Homolog 7 (CBX7))
    Épitope
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 37
    • 6
    • 6
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 29
    • 7
    • 1
    Lapin
    Clonalité
    • 24
    • 13
    Polyclonal
    Conjugué
    • 23
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp CBX7 est non-conjugé
    Application
    • 21
    • 10
    • 6
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Séquence
    LSRKKFPPRG PNLESHSHRR ELFLQEPPAP DVLQAAGEWE PAAQPPEEEA
    Attributs du produit
    This is a rabbit polyclonal antibody against CBX7. It was validated on Western Blot.
    Purification
    Affinity purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the C-terminal region of Human CBX7
    Top Product
    Discover our top product CBX7 Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    CBX7 (Chromobox Homolog 7 (CBX7))
    Autre désignation
    CBX7 (CBX7 Produits)
    Synonymes
    anticorps 1600014J01Rik, anticorps AI851678, anticorps D15Ertd417e, anticorps zgc:110152, anticorps chromobox 7, anticorps chromobox homolog 7a, anticorps CBX7, anticorps Cbx7, anticorps cbx7a
    Sujet
    CBX7 is a component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Promotes histone H3 trimethylation at 'Lys-9' (H3K9me3). Binds to trimethylated lysine residues in histones, and possibly also other proteins. Regulator of cellular lifespan by maintaining the repression of CDKN2A, but not by inducing telomerase activity.

    Protein Size: 251
    ID gène
    23492
    NCBI Accession
    NP_783640
    UniProt
    O95931
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