CBX7 anticorps (C-Term)
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- Antigène Voir toutes CBX7 Anticorps
- CBX7 (Chromobox Homolog 7 (CBX7))
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Épitope
- C-Term
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp CBX7 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- LSRKKFPPRG PNLESHSHRR ELFLQEPPAP DVLQAAGEWE PAAQPPEEEA
- Attributs du produit
- This is a rabbit polyclonal antibody against CBX7. It was validated on Western Blot.
- Purification
- Affinity purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human CBX7
- Top Product
- Discover our top product CBX7 Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- CBX7 (Chromobox Homolog 7 (CBX7))
- Autre désignation
- CBX7 (CBX7 Produits)
- Synonymes
- anticorps 1600014J01Rik, anticorps AI851678, anticorps D15Ertd417e, anticorps zgc:110152, anticorps chromobox 7, anticorps chromobox homolog 7a, anticorps CBX7, anticorps Cbx7, anticorps cbx7a
- Sujet
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CBX7 is a component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Promotes histone H3 trimethylation at 'Lys-9' (H3K9me3). Binds to trimethylated lysine residues in histones, and possibly also other proteins. Regulator of cellular lifespan by maintaining the repression of CDKN2A, but not by inducing telomerase activity.
Protein Size: 251 - ID gène
- 23492
- NCBI Accession
- NP_783640
- UniProt
- O95931
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