PRSS2 anticorps (Middle Region)

N° du produit ABIN5516528

Détail du produit anti-PRSS2 anticorps

Antigène: PRSS2 (Protease, serine, 2 (Trypsin 2) (PRSS2))

Épitope: Middle Region

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PRSS2 est non-conjugé

Application: Western Blotting (WB)

Séquence: EGNEQFINAA KIIRHPKYNS RTLDNDILLI KLSSPAVINS RVSAISLPTA

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human PRSS2

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur PRSS2

Antigène: PRSS2 (Protease, serine, 2 (Trypsin 2) (PRSS2))

Autre désignation: PRSS2 (PRSS2 Produits)

Synonymes: anticorps Dvir\\GJ21501, anticorps Dvtry-2, anticorps GJ21501, anticorps Try2, anticorps dvir_GLEANR_6854, anticorps TRY8, anticorps TRYP, anticorps Ta, anticorps Tesp4, anticorps Ptryss2, anticorps TRY2, anticorps TRYP2, anticorps trypsin-2, anticorps Trypsin-2, anticorps protease, serine 2, anticorps protease, serine, 2, anticorps trypsin II, anticorps CpipJ_CPIJ000771, anticorps CpipJ_CPIJ020109, anticorps Dvir\Try2, anticorps Prss2, anticorps PRSS2, anticorps trp-ii

Sujet: This gene belongs to the trypsin family of serine proteases and encodes anionic trypsinogen. It is part of a cluster of trypsinogen genes that are located within the T cell receptor beta locus. Enzymes of this family cleave peptide bonds that follow lysine or arginine residues. This protein is found at high levels in pancreatic juice and its upregulation is a characteristic feature of pancreatitis. This protein has also been found to activate pro-urokinase in ovarian tumors, suggesting a function in tumor invasion. In addition, this enzyme is able to cleave across the type II collagen triple helix in rheumatoid arthritis synovitis tissue, potentially participating in the degradation of type II collagen-rich cartilage matrix. Alternative splicing results in multiple transcript variants.

Alias Symbols: TRY2, TRY8, TRYP2

Protein Size: 247

ID gène: 5645

NCBI Accession: NM_002770, NP_002761

UniProt: P07478