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TAB2 anticorps (Middle Region)

TAB2 Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN5516590
  • Antigène Voir toutes TAB2 Anticorps
    TAB2 (TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 2 (TAB2))
    Épitope
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Middle Region
    Reactivité
    • 18
    • 8
    • 7
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 17
    • 3
    Lapin
    Clonalité
    • 19
    • 1
    Polyclonal
    Conjugué
    • 20
    Cet anticorp TAB2 est non-conjugé
    Application
    • 15
    • 7
    • 6
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Séquence
    SGSSQSSAHS QYNIQNISTG PRKNQIEIKL EPPQRNNSSK LRSSGPRTSS
    Attributs du produit
    This is a rabbit polyclonal antibody against TAB2. It was validated on Western Blot.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the middle region of Human TAB2
    Top Product
    Discover our top product TAB2 Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    TAB2 (TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 2 (TAB2))
    Autre désignation
    TAB2 (TAB2 Produits)
    Synonymes
    anticorps CHTD2, anticorps MAP3K7IP2, anticorps 1110030N06Rik, anticorps A530078N03Rik, anticorps Map3k7ip2, anticorps mKIAA0733, anticorps map3k7ip2, anticorps zgc:77446, anticorps TGF-beta activated kinase 1/MAP3K7 binding protein 2, anticorps TAB2, anticorps Tab2, anticorps tab2
    Sujet
    The protein encoded by this gene is an activator of MAP3K7/TAK1, which is required for for the IL-1 induced activation of nuclear factor kappaB and MAPK8/JNK. This protein forms a kinase complex with TRAF6, MAP3K7 and TAB1, and it thus serves as an adaptor that links MAP3K7 and TRAF6. This protein, along with TAB1 and MAP3K7, also participates in the signal transduction induced by TNFSF11/RANKl through the activation of the receptor activator of NF-kappaB (TNFRSF11A/RANK), which may regulate the development and function of osteoclasts. Studies of the related mouse protein indicate that it functions to protect against liver damage caused by chemical stressors. Mutations in this gene cause congenital heart defects, multiple types, 2 (CHTD2). Alternative splicing results in multiple transcript variants.

    Alias Symbols: TAB2, KIAA0733, MAP3K7IP2,

    Protein Interaction Partner: UBC, PIAS3, UBE2I, TRAF6, SUMO2, IRAK1, MAP3K7, TRIM38, SIK1, SIK3, TRIM22, NPM1, CST9L, SLC19A3, env, TAB1, NUMBL, IKBKG, FOSL1, ZBTB16, YWHAZ, VIM, TGM2, PPP2CB, IKBKB, GTF2I, FN1, HSP90AA1, BST2, MALT1, WDR34, APP, ESR1, MAP3K8, AR, TRIM5, TBL1XR1, MBD

    Protein Size: 536
    ID gène
    23118
    Pathways
    TCR Signaling, Signalisation TLR, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, Ubiquitin Proteasome Pathway
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