COQ6 anticorps (N-Term)

N° du produit ABIN5517062

Détail du produit anti-COQ6 anticorps

Antigène: COQ6 (Coenzyme Q6, Monooxygenase (COQ6))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Lapin, Boeuf (Vache), Chien, Cobaye, Cheval, Saccharomyces cerevisiae

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp COQ6 est non-conjugé

Application: Western Blotting (WB)

Séquence: ILLLEAGPKK VLEKLSETYS NRVSSISPGS ATLLSSFGAW DHICNMRYRA

Homologie: Cow: 93%, Dog: 86%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 93%, Yeast: 80%

Attributs du produit: This is a rabbit polyclonal antibody against COQ6. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of Human COQ6

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur COQ6

Antigène: COQ6 (Coenzyme Q6, Monooxygenase (COQ6))

Autre désignation: COQ6 (COQ6 Produits)

Synonymes: anticorps CGI10, anticorps COQ10D6, anticorps 5930427M12Rik, anticorps AW742344, anticorps zgc:153379, anticorps coq6, anticorps coenzyme Q6, monooxygenase, anticorps coenzyme Q6 monooxygenase, anticorps Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial, anticorps coenzyme Q6 monooxygenase L homeolog, anticorps COQ6, anticorps Coq6, anticorps coq-6, anticorps coq6, anticorps coq6.L

Sujet: The protein encoded by this gene belongs to the ubiH/COQ6 family. It is an evolutionarily conserved monooxygenase required for the biosynthesis of coenzyme Q10 (or ubiquinone), which is an essential component of the mitochondrial electron transport chain, and one of the most potent lipophilic antioxidants implicated in the protection of cell damage by reactive oxygen species. Knockdown of this gene in mouse and zebrafish results in decreased growth due to increased apoptosis. Mutations in this gene are associated with autosomal recessive coenzyme Q10 deficiency-6 (COQ10D6), which manifests as nephrotic syndrome with sensorineural deafness. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Alias Symbols: CGI10, COQ10D6

Protein Interaction Partner: SUMO1, UBC, NEDD8, APP, CDK2, ZBTB16, ARSE,

Protein Size: 443

ID gène: 51004

NCBI Accession: NM_182480, NP_872286