PHC3 anticorps (C-Term)

N° du produit ABIN5517248

Détail du produit anti-PHC3 anticorps

Antigène: PHC3 (Polyhomeotic Homolog 3 (PHC3))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PHC3 est non-conjugé

Application: Western Blotting (WB)

Séquence: LSRWNRKPDN QSLGHRGRRP SGPDGAAREH ILRQLPITYP SAEEDLASHE

Attributs du produit: This is a rabbit polyclonal antibody against PHC3. It was validated on Western Blot.

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Human PHC3

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur PHC3

Antigène: PHC3 (Polyhomeotic Homolog 3 (PHC3))

Autre désignation: PHC3 (PHC3 Produits)

Synonymes: anticorps EDR3, anticorps HPH3, anticorps E030046K01Rik, anticorps Edr3, anticorps Hph3, anticorps polyhomeotic homolog 3, anticorps polyhomeotic-like 3 (Drosophila), anticorps Phc3, anticorps PHC3

Sujet: PHC3 is a component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.

Alias Symbols: PHC3, EDR3, PH3,

Protein Interaction Partner: OGT, UBC, EED, RNF2, BMI1, SOX2, ALB, CBX2, PHC3, CBX8, CBX6, SCMH1, CBX4, PCGF2, SCML1, RING1, PHC2, PHC1, SUMO2,

Protein Size: 983

ID gène: 80012

NCBI Accession: XP_005247847

UniProt: Q8NDX5