RRAGA anticorps (C-Term)

N° du produit ABIN5517617

Détail du produit anti-RRAGA anticorps

Antigène: RRAGA (Ras-Related GTP Binding A (RRAGA))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RRAGA est non-conjugé

Application: Western Blotting (WB)

Séquence: CKEQRDVHRF EKISNIIKQF KLSCSKLAAS FQSMEVRNSN FAAFIDIFTS

Attributs du produit: This is a rabbit polyclonal antibody against RRAGA. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Human RRAGA

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur RRAGA

Antigène: RRAGA (Ras-Related GTP Binding A (RRAGA))

Autre désignation: RRAGA (RRAGA Produits)

Synonymes: anticorps FIP-1, anticorps FIP1, anticorps RAGA, anticorps 1300010C19Rik, anticorps AI255374, anticorps Raga, anticorps Ras related GTP binding A, anticorps Ras-related GTP binding A, anticorps RRAGA, anticorps Rraga

Sujet: RRAGA is a guanine nucleotide-binding protein forming heterodimeric Rag complexes required for the amino acid-induced relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. This is a crucial step in the activation of the TOR signaling cascade by amino acids. Involved in the RCC1/Ran-GTPase pathway. It may play a direct role in a TNF-alpha signaling pathway leading to induction of cell death. Also it may alternatively act as a cellular target for adenovirus E3-14.7K, an inhibitor of TNF-alpha functions, thereby affecting cell death.

Alias Symbols: RRAGA,

Protein Interaction Partner: RRAGC, RPTOR, STAU1, UBC, IL7R, ASAP1, CPSF2, CPSF3, CPSF1, CSTF2T, PAPOLA, CPSF4, CSTF3, CDC73, LAMTOR1, NOL8, RRAGA, RRAGD,

Protein Size: 313

ID gène: 10670

NCBI Accession: NP_006561

UniProt: Q7L523