ENY2 anticorps (N-Term)

N° du produit ABIN5517911

Détail du produit anti-ENY2 anticorps

Antigène: ENY2 (Enhancer of Yellow 2 Homolog (ENY2))

Épitope: N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ENY2 est non-conjugé

Application: Western Blotting (WB)

Séquence: QMRAAINQKL IETGERERLK ELLRAKLIEC GWKDQLKAHC KEVIKEKGLE

Attributs du produit: This is a rabbit polyclonal antibody against ENY2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of Human ENY2

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur ENY2

Antigène: ENY2 (Enhancer of Yellow 2 Homolog (ENY2))

Autre désignation: ENY2 (ENY2 Produits)

Synonymes: anticorps e(y)2, anticorps 1810057B09Rik, anticorps 6720481I12, anticorps DC6, anticorps Ey2, anticorps zgc:92656, anticorps enhancer of yellow 2 homolog L homeolog, anticorps ENY2, transcription and export complex 2 subunit, anticorps enhancer of yellow 2 homolog (Drosophila), anticorps eny2.L, anticorps ENY2, anticorps Eny2, anticorps eny2

Sujet: ENY2 is involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. It is required for nuclear receptor-mediated transactivation. The TREX-2 complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket). TREX-2 participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery.

Alias Symbols: ENY2, DC6,

Protein Interaction Partner: UBC, CIAPIN1, APP, ATXN7, USP22, MCM3AP, ATXN7L3, TRRAP, TAF10, KAT2A,

Protein Size: 101

ID gène: 56943

NCBI Accession: NP_064574

UniProt: Q9NPA8