NTRK3 anticorps (N-Term)

N° du produit ABIN5518697

Détail du produit anti-NTRK3 anticorps

Antigène: NTRK3 (Neurotrophic tyrosine Kinase, Receptor, Type 3 (NTRK3))

Épitope: AA 167-182, N-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NTRK3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: Rabbit IgG polyclonal antibody for NT-3 growth factor receptor(NTRK3) detection. Tested with WB, IHC-P in Human,Mouse,Rat.

Séquence: DIRWMQLWQE QGEAKL

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for NT-3 growth factor receptor(NTRK3) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: neurotrophic tyrosine kinase, receptor, type 3
Protein Name: NT-3 growth factor receptor

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the N-terminus of human TrkC(167-182aa DIRWMQLWQEQGEAKL), different from the related mouse and rat sequences by one amino acid.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat, The detection limit for NTRK3 is approximately 3 ng/lane under reducing conditions.
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide, Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Détails sur NTRK3

Antigène: NTRK3 (Neurotrophic tyrosine Kinase, Receptor, Type 3 (NTRK3))

Autre désignation: NTRK3 (NTRK3 Produits)

Sujet: NTRK3(Neurotrophic Tyrosine Kinase Receptor Type 3), also known as TRKC, is a protein that in humans is encoded by the NTRK3 gene. By PCR analysis of a somatic cell hybrid panel and by fluorescence in situ hybridization with the cDNA clone, McGregor et al.(1994) mapped the NTRK3 gene to 15q24-q25. Lamballe et al.(1991) isolated and characterized TRKC, a member of the TRK family of tyrosine protein kinase genes. They found that TRKC is preferentially expressed in the brain, in situ hybridization studies showed transcripts in the hippocampus, cerebral cortex, and the granular cell layer of the cerebellum. By functional studies in HeLa cells, Muinos-Gimeno et al.(2009) demonstrated that 5 miRNAs regulate the truncated form of NTRK3.

Synonyms: EC 2.7.10.1 antibody|ETS related protein neurotrophic receptor tyrosine kinase fusion antibody|ETV6 NTRK3 fusion antibody|GP145 TrkC antibody|gp145(trkC) antibody|GP145-TrkC antibody|GP145TrkC antibody|Neurotrophic tyrosine kinase receptor type 3 antibody|Neurotrophin 3 receptor antibody|NT 3 growth factor receptor antibody|NT 3 growth factor receptor precursor antibody|NT 3 receptor antibody|NT-3 growth factor receptor antibody|Ntrk3 antibody|NTRK3_HUMAN antibody|OTTHUMP00000192915 antibody|TRK C antibody|Trk-C antibody|TrkC tyrosine kinase antibody|Tyrosine kinase receptor C antibody

UniProt: Q16288

Pathways: Signalisation RTK, Neurotrophin Signaling Pathway, Regulation of Cell Size