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IL1RN anticorps (AA 26-177)

IL1RN Reactivité: Humain WB, ELISA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN5518923
  • Antigène Voir toutes IL1RN Anticorps
    IL1RN (Interleukin 1 Receptor Antagonist (IL1RN))
    Épitope
    • 28
    • 16
    • 11
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 26-177
    Reactivité
    • 80
    • 34
    • 16
    • 9
    • 9
    • 8
    • 7
    • 4
    • 4
    • 3
    Humain
    Hôte
    • 97
    • 34
    • 5
    • 3
    • 1
    • 1
    Lapin
    Clonalité
    • 104
    • 37
    Polyclonal
    Conjugué
    • 70
    • 29
    • 18
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp IL1RN est non-conjugé
    Application
    • 115
    • 52
    • 37
    • 25
    • 25
    • 21
    • 18
    • 18
    • 13
    • 13
    • 8
    • 6
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    Fonction
    Rabbit IgG polyclonal antibody for Interleukin-1 receptor antagonist protein(IL1RN) detection. Tested with WB, ELISA in Human.
    Réactivité croisée (Details)
    No cross reactivity with other proteins.
    Attributs du produit
    Rabbit IgG polyclonal antibody for Interleukin-1 receptor antagonist protein(IL1RN) detection. Tested with WB, ELISA in Human.
    Gene Name: interleukin 1 receptor antagonist
    Protein Name: Interleukin-1 receptor antagonist protein
    Purification
    Immunogen affinity purified.
    Immunogène
    E. coli-derived human IL1RA recombinant protein (Position: R26-E177). Human IL1RA shares 77% and 75.5% amino acid (aa) sequence identity with mouse and rat IL1RA, respectively.
    Isotype
    IgG
    Top Product
    Discover our top product IL1RN Anticorps primaire
  • Indications d'application
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
    ELISA: Concentration: 0.1-0.5 μg/mL, Tested Species: Human

    Notes: Tested Species: Species with positive results.
    Other applications have not been tested. Optimal dilutions should be determined by end users.
    Commentaires

    Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Concentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • Lu, Jiang, Cao, Zhang, Zhang, Ji, Gao: "TRAF6 upregulation in spinal astrocytes maintains neuropathic pain by integrating TNF-α and IL-1β signaling." dans: Pain, Vol. 155, Issue 12, pp. 2618-29, (2015) (PubMed).

  • Antigène
    IL1RN (Interleukin 1 Receptor Antagonist (IL1RN))
    Autre désignation
    IL1RN (IL1RN Produits)
    Synonymes
    anticorps DIRA, anticorps ICIL-1RA, anticorps IL-1RN, anticorps IL-1ra, anticorps IL-1ra3, anticorps IL1F3, anticorps IL1RA, anticorps IRAP, anticorps MVCD4, anticorps IRAP1, anticorps IL1RN, anticorps IL-1RA, anticorps F630041P17Rik, anticorps interleukin 1 receptor antagonist, anticorps interleukin 1 receptor antagonist-like, anticorps IL1RN, anticorps Il1rn, anticorps IL1RNL
    Sujet
    The interleukin-1 receptor antagonist (IL-1RA) is a protein that in humans is encoded by the IL1RN gene. The protein encoded by this gene is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Several alternatively spliced transcript variants encoding distinct isoforms have been reported.

    Synonyms: Interleukin-1 receptor antagonist protein, IL-1RN, IL-1ra, IRAP, ICIL-1RA, IL1 inhibitor, Anakinra, IL1RN, IL1F3, IL1RA
    ID gène
    3557
    UniProt
    P18510
    Pathways
    Signalisation NF-kappaB, Hormone Transport, Cancer Immune Checkpoints
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