CXCL12 anticorps
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- Antigène Voir toutes CXCL12 Anticorps
- CXCL12 (Chemokine (C-X-C Motif) Ligand 12 (CXCL12))
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Reactivité
- Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp CXCL12 est non-conjugé
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Application
- Western Blotting (WB)
- Fonction
- Rabbit IgG polyclonal antibody for SDF1 detection. Tested with WB in Mouse,Rat.
- Séquence
- RQVCIDPKLK WIQEYLEKAL NKRLKM
- Réactivité croisée (Details)
- No cross reactivity with other proteins.
- Attributs du produit
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Rabbit IgG polyclonal antibody for SDF1 detection. Tested with WB in Mouse,Rat.
Gene Name: chemokine (C-X-C motif) ligand 12
Protein Name: Stromal cell-derived factor 1 - Purification
- Immunogen affinity purified.
- Immunogène
- A synthetic peptide corresponding to a sequence of mouse SDF1 (RQVCIDPKLKWIQEYLEKALNKRLKM).
- Isotype
- IgG
- Top Product
- Discover our top product CXCL12 Anticorps primaire
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- Indications d'application
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Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users. - Commentaires
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Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- Concentration
- 500 μg/mL
- Buffer
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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iTRAQ-Based Quantitative Proteomic Comparison of Early- and Late-Passage Human Dermal Papilla Cell Secretome in Relation to Inducing Hair Follicle Regeneration." dans: PLoS ONE, Vol. 11, Issue 12, pp. e0167474, (2017) (PubMed).
: "Treatment of radiation-induced acute intestinal injury with bone marrow-derived mesenchymal stem cells." dans: Experimental and therapeutic medicine, Vol. 11, Issue 6, pp. 2425-2431, (2016) (PubMed).
: "Tacrolimus promotes hepatocellular carcinoma and enhances CXCR4/SDF‑1α expression in vivo." dans: Molecular medicine reports, Vol. 10, Issue 2, pp. 585-92, (2015) (PubMed).
: "Construction of a CXCL12-KDEL fusion gene to inhibit head and neck squamous cell carcinoma metastasis by intracellular sequestration of CXCR4." dans: BioMed research international, Vol. 2015, pp. 195828, (2015) (PubMed).
: "Gene expression profile analyze the molecular mechanism of CXCR7 regulating papillary thyroid carcinoma growth and metastasis." dans: Journal of experimental & clinical cancer research : CR, Vol. 34, pp. 16, (2015) (PubMed).
: "Mesenchymal stem cell transplantation enhancement in myocardial infarction rat model under ultrasound combined with nitric oxide microbubbles." dans: PLoS ONE, Vol. 8, Issue 11, pp. e80186, (2013) (PubMed).
: "CXCR4/SDF-1 axis is involved in lymph node metastasis of gastric carcinoma." dans: World journal of gastroenterology, Vol. 17, Issue 19, pp. 2389-96, (2011) (PubMed).
: "Chemokine CXCL12 and its receptor CXCR4 expression are associated with perineural invasion of prostate cancer." dans: Journal of experimental & clinical cancer research : CR, Vol. 27, pp. 62, (2009) (PubMed).
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iTRAQ-Based Quantitative Proteomic Comparison of Early- and Late-Passage Human Dermal Papilla Cell Secretome in Relation to Inducing Hair Follicle Regeneration." dans: PLoS ONE, Vol. 11, Issue 12, pp. e0167474, (2017) (PubMed).
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- Antigène
- CXCL12 (Chemokine (C-X-C Motif) Ligand 12 (CXCL12))
- Autre désignation
- CXCL12 (CXCL12 Produits)
- Synonymes
- anticorps IRH, anticorps PBSF, anticorps SCYB12, anticorps SDF1, anticorps TLSF, anticorps TPAR1, anticorps CINC-1, anticorps Gro1, anticorps Pbsf, anticorps Scyb12, anticorps Sdf1, anticorps Tlsf, anticorps Tpar1, anticorps Fsp, anticorps KC, anticorps Mgsa, anticorps N51, anticorps Scyb1, anticorps gro, anticorps sdf-1, anticorps sdf1, anticorps xSDF-1, anticorps SDF-1, anticorps cxcl12, anticorps sdf-1a, anticorps sdf1a, anticorps wu:fa55e10, anticorps wu:fc16h12, anticorps wu:fj84c02, anticorps C-X-C motif chemokine ligand 12, anticorps C-X-C motif chemokine ligand 1, anticorps chemokine (C-X-C motif) ligand 12, anticorps chemokine (C-X-C motif) ligand 1, anticorps C-X-C motif chemokine ligand 12 L homeolog, anticorps chemokine (C-X-C motif) ligand 12a (stromal cell-derived factor 1), anticorps CXCL12, anticorps cxcl12, anticorps Cxcl1, anticorps Cxcl12, anticorps cxcl12.L, anticorps cxcl12a
- Sujet
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The stromal cell-derived factor 1 (SDF1), also known as C-X-C motif chemokine 12 (CXCL12), is a chemokine protein that in humans is encoded by the CXCL12 gene on chromosome 10. This antimicrobial gene encodes a stromal cell-derived alpha chemokine member of the intercrine family. The encoded protein functions as the ligand for the G-protein coupled receptor, chemokine (C-X-C motif) receptor 4, and plays a role in many diverse cellular functions, including embryogenesis, immune surveillance, inflammation response, tissue homeostasis, and tumor growth and metastasis. Mutations in this gene are associated with resistance to human immunodeficiency virus type 1 infections. Multiple transcript variants encoding different isoforms have been found for this gene.
Synonyms: Stromal cell-derived factor 1, SDF-1, hSDF-1, C-X-C motif chemokine 12, Intercrine reduced in hepatomas, IRH, hIRH, Pre-B cell growth-stimulating factor, PBSF, SDF-1-beta(3-72), SDF-1-alpha(3-67), CXCL12, SDF1, SDF1A, SDF1B - ID gène
- 20315
- UniProt
- P48061
- Pathways
- Regulation of Cell Size, CXCR4-mediated Signaling Events, Negative Regulation of intrinsic apoptotic Signaling
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