Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

Aurora A anticorps (C-Term)

AURKA Reactivité: Humain WB, IF, FACS Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN5530244
  • Antigène Voir toutes Aurora A (AURKA) Anticorps
    Aurora A (AURKA) (Aurora Kinase A (AURKA))
    Épitope
    • 28
    • 22
    • 8
    • 8
    • 8
    • 7
    • 7
    • 6
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 364-392, C-Term
    Reactivité
    • 127
    • 74
    • 42
    • 20
    • 18
    • 14
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    Humain
    Hôte
    • 123
    • 21
    • 1
    Lapin
    Clonalité
    • 110
    • 34
    Polyclonal
    Conjugué
    • 83
    • 10
    • 8
    • 7
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Aurora A est non-conjugé
    Application
    • 106
    • 59
    • 37
    • 26
    • 19
    • 15
    • 12
    • 11
    • 6
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
    Immunogène
    This Aurora-A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 364-392 amino acids from the C-terminal region of human Aurora-A.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product AURKA Anticorps primaire
  • Indications d'application
    For WB starting dilution is: 1:1000

    For IF starting dilution is: 1:10~50

    For FACS starting dilution is: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    2 mg/mL
    Buffer
    Supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Antigène
    Aurora A (AURKA) (Aurora Kinase A (AURKA))
    Autre désignation
    Aurora-A (AURKA Produits)
    Synonymes
    anticorps AIK, anticorps ARK1, anticorps AURA, anticorps AURORA2, anticorps BTAK, anticorps PPP1R47, anticorps STK15, anticorps STK6, anticorps STK7, anticorps AIRK1, anticorps AU019385, anticorps AW539821, anticorps Ark1, anticorps Aurora-A, anticorps Ayk1, anticorps IAK, anticorps IAK1, anticorps Stk6, anticorps 87A7-9/2, anticorps Aur-A, anticorps AurA, anticorps CG3068, anticorps Dmel\\CG3068, anticorps aur-A, anticorps aurA, anticorps ck10, anticorps ck[10], anticorps l(3)87Ac, anticorps l(3)ck10, anticorps ARK-1, anticorps Eg2, anticorps aik, anticorps ark1, anticorps aur-a, anticorps aura, anticorps aurka-a, anticorps aurora2, anticorps btak, anticorps stk15, anticorps stk6, anticorps stk7, anticorps pEg2, anticorps wu:fb37c10, anticorps wu:fc02c02, anticorps zgc:100912, anticorps AURKA, anticorps aurka, anticorps aurora kinase A, anticorps aurora A, anticorps aurora kinase A L homeolog, anticorps hypothetical protein, anticorps aurora kinase A S homeolog, anticorps AURKA, anticorps Aurka, anticorps aurA, anticorps aurka.L, anticorps aurka, anticorps Aurora-A, anticorps aurka.S
    Sujet
    Chromosomal segregation during mitosis as well as meiosis is regulated by kinases and phosphatases. The Aurora kinases, members of the Ser/Thr protein kinase family, associate with microtubules during chromosome movement and segregation. Auroria kinase A may play a role in cell cycle regulation during anaphase and/or telophase, in relation to the function of the centrosome/spindle pole region during chromosome segregation. It may be involved in microtubule formation and/or stabilization. This protein has also been postulated to play a key role during tumor development and progression. Aurora kinase A localizes on centrosomes in interphase cells and at each spindle pole in mitosis. It is highly expressed in testis, weakly in skeletal muscle, thymus and spleen, and also highly expressed in colon, ovarian, prostate, neuroblastoma, breast and cervical cancer cell lines. Expression is cell-cycle regulated, low in G1/S, accumulates during G2/M, and decreases rapidly afterward. Defects in Aurora kinase A are responsible for numerical centrosome aberrations including aneuploidy.
    Poids moléculaire
    46 kDa
    ID gène
    6790
    UniProt
    O14965
    Pathways
    Cycle Cellulaire, Asymmetric Protein Localization
Vous êtes ici:
Support technique