This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogène
This BRMS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 48-77 amino acids from the N-terminal region of human BRMS1.
BRMS1
Reactivité: Humain, Souris, Rat
WB, ELISA, IHC, IHC (p)
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
For WB starting dilution is: 1:1000
Restrictions
For Research Use only
Format
Liquid
Concentration
0.5 mg/mL
Buffer
Supplied in PBS with 0.09 % (W/V) sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C,-20 °C
Stockage commentaire
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Antigène
BRMS1
(Breast Cancer Metastasis Suppressor 1 (BRMS1))
anticorps MGC98869, anticorps BRMS1, anticorps BRMS1L, anticorps AV003220, anticorps AW554636, anticorps si:zc188c22.3, anticorps si:zc194c5.2, anticorps wu:fb57b08, anticorps zgc:56414, anticorps breast cancer metastasis suppressor 1, anticorps breast cancer metastasis-suppressor 1, anticorps breast cancer metastasis suppressor 1 L homeolog, anticorps BRMS1, anticorps Brms1, anticorps brms1.L, anticorps brms1
Sujet
This gene reduces the metastatic potential, but not the tumorogenicity, of human breast cancer and melanoma cell lines. The protein encoded by this gene localizes primarily to the nucleus and is a component of the mSin3a family of histone deacetylase complexes (HDAC). The protein contains two coiled-coil motifs and several imperfect leucine zipper motifs. Alternative splicing results in two transcript variants encoding different isoforms.