DUSP14 anticorps (C-Term)

N° du produit ABIN5531046

Détail du produit anti-DUSP14 anticorps

Antigène: DUSP14 (Dual Specificity Phosphatase 14 (DUSP14))

Épitope: AA 168-198, C-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DUSP14 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Immunogène: This DUSP14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 168-198 amino acids from the C-terminal region of human DUSP14.

Isotype: Ig Fraction

Information d'application

Indications d'application: For IHC-P starting dilution is: 1:50~100

For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 2 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur DUSP14

Antigène: DUSP14 (Dual Specificity Phosphatase 14 (DUSP14))

Autre désignation: DUSP14 (DUSP14 Produits)

Synonymes: anticorps MGC84083, anticorps zgc:101746, anticorps DUSP14, anticorps mkp-l, anticorps mkp6, anticorps MKP-L, anticorps MKP6, anticorps 1110014C10Rik, anticorps 2310042C07Rik, anticorps D11Ertd395e, anticorps Mkp6, anticorps dual specificity phosphatase 14, anticorps dual specificity phosphatase 14 L homeolog, anticorps DUSP14, anticorps dusp14.L, anticorps dusp14, anticorps Dusp14

Sujet: DUSP14 is involved in the inactivation of MAP kinases. This proein dephosphorylates ERK, JNK and p38 MAP-kinases. In addition to antigen recognition by the T-cell receptor, T-cell activation requires a second signal from a costimulatory receptor, such as CD28, which interacts with B7-1 (CD80) and B7-2 (CD86) ligands on antigen-presenting cells. CD28 costimulation induces transcription of interleukin-2 and stabilizes newly synthesized IL2 through the activation of mitogen-activated protein kinases (MAPKs), such as ERK and JNK, and the subsequent creation of AP1 transcription factor. DUSP14 is a negative regulator of CD28 signaling.

Poids moléculaire: 22 kDa

ID gène: 11072

UniProt: O95147